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Three-Year Follow-up of a Novel Aqueous Humor MicroShunt
Surgery with the InnFocus MicroShunt transscleral aqueous drainage tube with Mitomycin C achieved IOP control in the low teens in most subjects up to 3 years of follow-up with only transient adverse events occurring within the first 3 months after surgery.
The development of a micro‐shunt made from poly(styrene‐block‐isobutylene‐block‐styrene) to treat glaucoma
- L. Pinchuk, I. Riss, J. Parel
- MedicineJournal of biomedical materials research. Part B…
- 18 September 2015
The InnFocus MicroShunt®, which is a minimally invasive glaucoma drainage micro‐tube used to shunt aqueous humor from the anterior chamber of the eye to a flap formed under the conjunctiva and Tenon's Capsule, is summarized.
Medical applications of poly(styrene-block-isobutylene-block-styrene) ("SIBS").
A review of the biostability and carcinogenicity of polyurethanes in medicine and the new generation of 'biostable' polyurethanes.
- L. Pinchuk
- Medicine, Materials ScienceJournal of biomaterials science. Polymer edition
Polyurethanes are very versatile materials which have been used in the body for over 20 years. In fact, there are probably more scientific papers describing these materials and modifications of these…
The use of poly(styrene-block-isobutylene-block-styrene) as a microshunt to treat glaucoma
The integration of SIBS into a glaucoma drainage device is summarized and its functionality with clinical success over a 2-year period is confirmed.
In-vivo assessment of a novel polymer (SIBS) trileaflet heart valve.
- Q. Wang, A. McGoron, R. Bianco, Y. Kato, L. Pinchuk, R. Schoephoerster
- MedicineThe Journal of heart valve disease
- 1 July 2010
The physical properties of SIBS must be improved in order to provide the structural integrity required for long-term in-vivo use in the form of a heart valve.
Flow-induced platelet activation in a St. Jude mechanical heart valve, a trileaflet polymeric heart valve, and a St. Jude tissue valve.
- W. Yin, S. Gallocher, L. Pinchuk, R. Schoephoerster, J. Jesty, D. Bluestein
- Medicine, BiologyArtificial organs
- 1 October 2005
A new polymer (Quatromer) trileaflet design was tested for its thrombogenic potential and was compared to that of existing prosthetic heart valves routinely implanted in patients: a St. Jude Medical bileaflet mechanical heart valve (MHV) and a St Jude porcine bioprosthetic tissue valve.
Minimally Invasive Glaucoma Surgery with a New Ab-externo Subconjunctival Bypass – Current Status and Review of Literature
Although more robust data are needed, these first studies suggest that the PRESERFLO MicroShunt is a promising new, minimally invasive procedure for glaucoma.
A novel polymer for potential use in a trileaflet heart valve.
- S. Gallocher, Andrés Aguirre, V. Kasyanov, L. Pinchuk, R. Schoephoerster
- Materials ScienceJournal of biomedical materials research. Part B…
- 1 November 2006
Quatromer is shown to have suitable hemocompatibility and mechanical durability for use in polymer trileaflet heart valves, and fiber reinforcement can effectively be used to tailor the mechanical properties.
A newly designed glaucoma drainage implant made of poly(styrene-b-isobutylene-b-styrene): biocompatibility and function in normal rabbit eyes.
This new GDI made of SIBS is clinically biocompatible in the rabbit and maintained 100% patency at 6 months and would prevent the feared complication of hypotony and will decrease the amount of subconjunctival fibrosis.