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Calcitriol Protects against the Dopamine‐ and Serotonin‐Depleting Effects of Neurotoxic Doses of Methamphetamine
Abstract:  Repeated methamphetamine (METH) administration to animals can result in long‐lasting decreases in brain dopamine (DA) and serotonin (5‐HT) content. Calcitriol, the active metabolite ofExpand
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HIV-1 protein Tat potentiation of methamphetamine-induced decreases in evoked overflow of dopamine in the striatum of the rat
HIV-1 infection of the brain can lead to the development of clinical syndromes reminiscent of Parkinson's disease, suggesting that HIV infection may damage nigrostriatal dopamine (DA) neurons.Expand
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Neurturin Effects on Nigrostriatal Dopamine Release and Content: Comparison with GDNF
Neurturin (NTN) is a member of the glial cell line-derived neurotrophic factor (GDNF) family; and, while GDNF has been shown to increase dopamine (DA) release in normal animals, the ability of NTN toExpand
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Calcitriol Promotes Augmented Dopamine Release in the Lesioned Striatum of 6-Hydroxydopamine Treated Rats
Current therapies for Parkinson’s disease (PD) offer symptomatic relief but do not provide a cure or slow the disease process. Treatments that could halt progression of the disease or help restoreExpand
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Protection by GDNF and Other Trophic Factors Against the Dopamine‐Depleting Effects of Neurotoxic Doses of Methamphetamine
Abstract:  Repeated methamphetamine (METH) administration to animals can result in long‐lasting decreases in striatal dopamine (DA) content. It has previously been shown that glial cell line‐derivedExpand
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Evoked dopamine overflow is augmented in the striatum of calcitriol treated rats
Calcitriol, the active metabolite of vitamin D, has been shown to have significant effects on the brain. These actions include reducing the severity of some central nervous system lesions, possiblyExpand
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Reductions in spontaneous locomotor activity in aged male, but not female, rats in a model of early Parkinson's disease
The excessive loss of dopamine (DA) neurons that occurs with Parkinson's disease is usually confined to older individuals. While 6-hydroxydopamine (6-OHDA) is often used in animal models of DA neuronExpand
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Lymphocyte subset analysis by Boolean algebra: a phenotypic approach using a cocktail of 5 antibodies and 3 color immunofluorescence.
Commercial reagent kits for the evaluation of leukocyte subsets involve the staining of a panel of up to six tubes using combinations of pre-mixed fluorescein isothiocyanate (FITC) andExpand
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Oxidative stress‐induced retinal damage is prevented by mild hypothermia in an ex vivo model of cultivated porcine retinas
Hydrogen peroxide (H2O2) can be used in vitro to simulate oxidative stress. In retinal organ cultures, H2O2 induces strong neurodegeneration of the retina. It is known that oxidative stress plays aExpand
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