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Antihypertensive and natriuretic effects of CGS 30440, a dual inhibitor of angiotensin-converting enzyme and neutral endopeptidase 24.11.
- R. Chatelain, R. Ghai, +5 authors C. Fink
- Chemistry, Medicine
- The Journal of pharmacology and experimental…
- 1 March 1998
Dual angiotensin-converting enzyme (ACE)/neutral endopeptidase (NEP) inhibitors, by decreasing angiotensin-II production and by preventing the degradation of atrial natriuretic peptide (ANP), may be… Expand
Effects of the novel dual inhibitor of neutral endopeptidase and angiotensin-converting enzyme, CGS 30440, on blood pressure and cardiac hypertrophy in spontaneously hypertensive rats.
- R. Webb, M. Abramson, M. Beil, L. Odorico, R. Chatelain
- Journal of cardiovascular pharmacology
- 1 November 1997
This study examined the long-term effects of CGS 30440 on blood pressure, heart rate, cardiac hypertrophy, and urinary parameters in conscious spontaneously hypertensive rats (SHRs) and Wistar-Kyoto… Expand
Universal health coverage in Latin America 3 Social determinants of health, universal health coverage, and sustainable development: case studies from Latin American countries
Many intrinsically related determinants of health and disease exist, including social and economic status, education, employment, housing, and physical and environmental exposures. These factors… Expand