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Neuroprotection by the α2-adrenoceptor agonist, dexmedetomidine, in rat focal cerebral ischemia
TLDR
The results suggest that dexmedetomidine reduced ischemic volume despite causing a minor increase in blood glucose concentrations and hypotension, and its neuroprotective efficacy was better than that produced by CGS-19775, and dexmedETomidine was safer with respect to kidney toxicity when compared to NBQX. Expand
Neuroprotection by the alpha2-adrenoceptor agonist, dexmedetomidine, in rat focal cerebral ischemia.
TLDR
The results suggest that dexmedetomidine reduced ischemic volume despite causing a minor increase in blood glucose concentrations and hypotension, and its neuroprotective efficacy was better than that produced by CGS-19775, and dexmedetic was safer with respect to kidney toxicity when compared to NBQX. Expand
In vivo detection of vascular adhesion protein-1 in experimental inflammation.
TLDR
Results suggest that VAP-1 is both an optimal candidate for anti-adhesive therapy and a potential target molecule for imaging inflammation. Expand
The Proliferation in Uterine Compartments of Intact Rats of Two Different Strains Exposed to High Doses of Tamoxifen or Toremifene
TLDR
Uterine cell proliferation was studied in intact Sprague-Dawley (SD) and Fischer 344 (F344) rats exposed to the antiestrogens tamoxifen and toremifene to suggest that this hyperplastic epithelium represents remnants from the glandular epithelia. Expand
Damage Caused by Tw o Finnish Mushrooms, Cortinarius speciosissimus and Cortinarius gentilis on the Rat Kidney
TLDR
The toxicity of two mushroom species found in Finland, Cortinarius speciosissimus and Cortinaria gentilis, on the rat was studied and it was demonstrated that both species caused renal damage. Expand
Nephrotoxicity of Cortinarius speciosissimus: a histological and enzyme histochemical study.
TLDR
A high activity of arginine residue cleaving aminopeptidase was observed in the inflammatory focuses located in the outer medullary zone, showing the important role of this enzyme in kidney inflammation. Expand
A two-year dietary carcinogenicity study of the antiestrogen toremifene in Sprague-Dawley rats.
TLDR
It is indicated that toremifene is an efficient antiestrogen in long-term treatment, is well tolerated and has no tumorigenic potential in rats. Expand
Effect of hyperlipidaemic diet and clofibrate treatment on rat erythrocyte lipids.
TLDR
The results suggest that the erythrocyte cell membrane can increase its cholesterol content and possibly play a role in cholesterol transport. Expand
Pharmacokinetic studies of the antiarrhythmic drugs ajmaline and N-propylajmaline bitartrate in dogs.
A rapid, sensitive fluorometric method for the determination of ajmaline and N-propylajmaline (NPA) was used to follow serum concentrations after an i.v. administration of ajmaline, after an oralExpand
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