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The carriage of risk variants of CDKAL1 impairs beta-cell function in both diabetic and non-diabetic patients and reduces response to non-sulfonylurea and sulfonylurea agonists of the pancreatic KATP…

• Dimitry Alexandrovich Chistiakov, Viktor A. Potapov, Svetlana A. Smetanina, L. N. Bel’chikova, Lyudmila A. Suplotova, Valery V. Nosikov
• Acta Diabetologica
• 2011

On chromosome 6q22.3, a cluster of single-nucleotide polymorphisms located in intron 5 of the cyclin-dependent kinase 5 (CDK5) regulatory subunit-associated protein 1-like 1 (CDKAL1) gene were shown… (More)

TCF7L2 rs12255372 and SLC30A8 rs13266634 confer susceptibility to type 2 diabetes in a Russian population

• Viktor A. Potapov, M. N. Shamkhalova, +4 authors Valery V. Nosikov
• Russian Journal of Genetics
• 2010

Genes TCF7L2 and SLC30A8, encoding transcription factor-4 and transmembrane zinc transporter-8, respectively, play an important role in the regulation of development, proliferation, and pancreatic β… (More)

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