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Statin-Induced Inhibition of MCF-7 Breast Cancer Cell Proliferation is Related to Cell Cycle Arrest and Apoptotic and Necrotic Cell Death Mediated by an Enhanced Oxidative Stress
The results suggest that the cytotoxic effect observed is mediated by an oxidative stress. Expand
Statins Inhibit the Proliferation and Induce Cell Death of Human Papilloma Virus Positive and Negative Cervical Cancer Cells
The results suggest that statins exert anti-tumoral effects on cervical cancer through inhibition of cell proliferation and induction of cell death and oxidative stress, and could be an aid in the treatment of cervical cancer. Expand
Influenza control in the 21st century: Optimizing protection of older adults.
While it is clear that vaccines with greater immunogenicity are required for older adults, and that adjuvanted vaccines may offer a short-term solution, further research is required to exploit the many other new technologies. Expand
Apolipoprotein E polymorphism in the Indian and Mestizo populations of Mexico.
The findings suggest that the APOE*2 allele was absent in humans from northern Asia who settled in the Arctic and populated the American continent. Expand
Ceramide promotes the death of human cervical tumor cells in the absence of biochemical and morphological markers of apoptosis.
C8-ceramide markedly reduced the tumor cell number after 48 h of treatment, an effect that endured even after the removal of C8- Aceramide, and the possible application of ceramide in the treatment of early stages of cervical cancer is discussed. Expand
Intracellular expression of interleukin‐4 and interferon‐γ by a Mycobacterium tuberculosis antigen‐stimulated CD4+ CD57+ T‐cell subpopulation with memory phenotype in tuberculosis patients
The findings suggest that the majority of CD4+ CD57+ T cells correspond to a phenotype of activated memory T cells, which is associated with memory cells. Expand
Inhalation of vanadium pentoxide and its toxic effects in a mouse model
Abstract Vanadium pentoxide (V 2 O 5 ) is one of the compounds bound to the suspended material found in the atmosphere and classified as particulate matter. The main source of these pollutants is theExpand
Incubation with DNase I inhibits tumor cell proliferation.
The results suggest that the use of a DNA nuclease might have some benefits in the treatment of cancer since it inhibits cell growth, probably by inducing autoschizis. Expand
Chronic hypothyroidism induces abnormal structure of high-density lipoproteins and impaired kinetics of apolipoprotein A-I in the rat.
Chronic hypothyroidism in rat a species that lacks cholesteryl ester transfer protein (CETP) activity is characterized by low HDL-C and apo A-I plasma levels as a result of a low apoA-I production rate that exceeds a decreased FCR. Expand
17β-estradiol inhibits the adhesion of leukocytes in TNF-α stimulated human endothelial cells by blocking IL-8 and MCP-1 secretion, but not its transcription
17β-estradiol modifies the adhesion of leukocytes to endothelial cells by inhibiting the secretion, but not the gene transcription, of proinflammatory chemokines. Expand