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Ezh2 Regulates Transcriptional and Posttranslational Expression of T-bet and Promotes Th1 Cell Responses Mediating Aplastic Anemia in Mice
Acquired aplastic anemia (AA) is a potentially fatal bone marrow (BM) failure syndrome. IFN-γ–producing Th1 CD4+ T cells mediate the immune destruction of hematopoietic cells, and they are central to… Expand
Ezh2 phosphorylation state determines its capacity to maintain CD8+ T memory precursors for antitumor immunity
Memory T cells sustain effector T-cell production while self-renewing in reaction to persistent antigen; yet, excessive expansion reduces memory potential and impairs antitumor immunity. Epigenetic… Expand
Identification of salt-tolerant QTLs with strong genetic background effect using two sets of reciprocal introgression lines in rice.
Effect of genetic background on detection of quantitative trait locus (QTL) governing salinity tolerance (ST) was studied using two sets of reciprocal introgression lines (ILs) derived from a cross… Expand
Digital Gene Expression Tag Profiling Analysis of the Gene Expression Patterns Regulating the Early Stage of Mouse Spermatogenesis
Detailed characterization of the gene expression patterns in spermatogonia and primary spermatocytes is critical to understand the processes which occur prior to meiosis during normal… Expand
Optimized grating as an ultra-narrow band absorber or plasmonic sensor.
- L. Meng, Ding Zhao, Z. Ruan, Q. Li, Yuanqing Yang, M. Qiu
- Materials Science, Medicine
- Optics letters
- 1 March 2014
Lamellar gratings are investigated via temporal coupled-mode theory and numerical simulations. Total absorption can be achieved by an optimized grating with shallow grooves under normal incidence and… Expand
Polarization-sensitive perfect absorbers at near-infrared wavelengths.
Three different types of polarization-sensitive perfect absorbers are designed and numerically investigated. The bottle-like and the cup-like absorbers are narrowband absorbers, which strongly absorb… Expand
The role of P2X7 receptor in ATP-mediated human leukemia cell death: calcium influx-independent.
- X. Zhang, L. Meng, +6 authors Dong An
- Biology, Medicine
- Acta biochimica et biophysica Sinica
- 1 May 2009
Activation of the P2X7 receptor leads to a rapid, bidirectional flux of cations, causing broad range of biological responses including cytotoxicity. However, the mechanism of P2X7-mediated… Expand
Chaperones-assisted soluble expression and maturation of recombinant Co-type nitrile hydratase in Escherichia coli to avoid the need for a low induction temperature.
Nitrile hydratase (NHase) is an important industrial enzyme that biosynthesizes high-value amides. However, most of NHases expressed in Escherichia coli easily aggregate to inactive inclusion bodies… Expand
Direct and quasi-direct band gap silicon allotropes with remarkable stability.
- C. He, C. Zhang, +4 authors J. Zhong
- Chemistry, Medicine
- Physical chemistry chemical physics : PCCP
- 10 June 2015
In our present work, five previously proposed sp(3) carbon crystals were suggested as silicon allotropes and their stabilities, electronic and optical properties were investigated using the… Expand
Simultaneous improvement in cold tolerance and yield of temperate japonica rice (Oryza sativa L.) by introgression breeding
To combine high yield and improved cold tolerance (CT) in a japonica rice variety, ‘Chaoyou1’ (CY1), 324 BC2F5 introgression lines (ILs) selected for CT from 11 CY1 BC2F4 populations were evaluated… Expand