• Publications
  • Influence
History of the Rochester Epidemiology Project.
  • L. Melton
  • Medicine
    Mayo Clinic proceedings
  • 1 March 1996
TLDR
The Rochester Epidemiology Project is a unique medical records-linkage system that encompasses the care delivered to residents of Rochester and Olmsted County, Minnesota and is able to provide accurate incidence data for almost any serious condition and to support population-based analytic studies of disease causes and outcomes.
Risk factors for deep vein thrombosis and pulmonary embolism: a population-based case-control study.
TLDR
Hospital or nursing home confinement, surgery, trauma, malignant neoplasm, chemotherapy, neurologic disease with paresis, central venous catheter or pacemaker, varicose veins, and superficial vein thrombosis are independent and important risk factors for VTE.
Trends in the incidence of deep vein thrombosis and pulmonary embolism: a 25-year population-based study.
TLDR
The incidence of pulmonary embolism has decreased over time, the incidence of deep vein thrombosis remains unchanged for men and is increasing for older women, and the need for more accurate identification of patients at risk for venous thromboembolism is emphasized.
Medical Expenditures for the Treatment of Osteoporotic Fractures in the United States in 1995: Report from the National Osteoporosis Foundation
TLDR
Although the majority of U.S. health care expenditures for the treatment of osteoporotic fractures were for white women, one‐fourth of the total was borne by other population subgroups.
Prevalence of monoclonal gammopathy of undetermined significance.
TLDR
Among residents of Olmsted County, Minnesota, MGUS was found in 3.2% of persons 50 years of age or older and 5.3 percent of persons 70 years ofAge or older, which are higher in men than in women.
Prevalence and clinical spectrum of gastroesophageal reflux: a population-based study in Olmsted County, Minnesota.
TLDR
Symptoms of reflux are common among white men and women who are 25-74 years of age and heartburn and acid regurgitation are significantly associated with chest pain, dysphagia, dyspepsia, and globus sensation.
Clinical course and prognosis of smoldering (asymptomatic) multiple myeloma.
TLDR
The risk of progression from smoldering multiple myeloma to symptomatic disease is related to the proportion of bone marrow plasma cells and the serum monoclonal protein level at diagnosis.
A long-term study of prognosis in monoclonal gammopathy of undetermined significance.
TLDR
The risk of progression of MGUS to multiple myeloma or related disorders is about 1 percent per year, and the initial concentration of serum monoclonal protein was a significant predictor of progression at 20 years.
A reference standard for the description of osteoporosis.
TLDR
This paper proposes that the reference standard should be based on bone mineral density (BMD) measurement made at the femoral neck with dual-energy X-ray absorptiometry (DXA), which has been the most extensively validated, and provides a gradient of fracture risk as high as or higher than that of many other techniques.
Population‐Based Study of Herpes Zoster and Its Sequelae
TLDR
The dermatomal distribution of herpes zoster observed in Rochester was quite similar to previous studies, despite their inherent biases in case ascertainment, except for a lower proportion with cranial nerve zoster.
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