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Transmission of Multidrug-Resistant and Drug-Susceptible Tuberculosis within Households: A Prospective Cohort Study
Background The “fitness” of an infectious pathogen is defined as the ability of the pathogen to survive, reproduce, be transmitted, and cause disease. The fitness of multidrug-resistant tuberculosisExpand
Elastin-like recombinamers as substrates for retinal pigment epithelial cell growth.
The aim of this study is to investigate the use of elastin-like recombinamers (ELRs) as a substrate that can maintain the growth, phenotype, and functional characteristics of retinal pigmentExpand
Trkb Signaling in Pericytes Is Required for Cardiac Microvessel Stabilization
Pericyte and vascular smooth muscle cell (SMC) recruitment to the developing vasculature is an important step in blood vessel maturation. Brain-derived neurotrophic factor (BDNF), expressed byExpand
Considering technical and financial impact in the selection of security countermeasures against Advanced Persistent Threats (APTs)
We propose in this paper an approach to evaluate and select security countermeasures based on industrial evaluation and simulations of the financial and technical impact associated to a group of countermeasures. Expand
Immunomodulatory nanoparticles from elastin-like recombinamers: single-molecules for tuberculosis vaccine development.
This study investigates both the physicochemical properties and immunogenicity of a genetically engineered elastin-like block corecombinamer (ELbcR) containing a major membrane protein sequence fromExpand
Therapeutic Benefit of Selective Inhibition of p110α PI3-Kinase in Pancreatic Neuroendocrine Tumors
Purpose: Mutations in the PI3K pathway occur in 16% of patients with pancreatic neuroendocrine tumors (PanNETs), which suggests that these tumors are an exciting setting for PI3K/AKT/mTORExpand
Tuberculosis Diagnosis and Multidrug Resistance Testing by Direct Sputum Culture in Selective Broth without Decontamination or Centrifugation
ABSTRACT Tuberculosis culture usually requires sputum decontamination and centrifugation to prevent cultures from being overgrown by contaminating bacteria and fungi. However, decontaminationExpand
Bioactive substrates for human retinal pigment epithelial cell growth from elastin-like recombinamers.
The aim of this study was to investigate the use of bioactive RGD-containing elastin-like recombinamers (ELR-RGDs) as a substrate that can maintain human retinal pigment epithelial cell (hRPE)Expand
The Association between Mycobacterium Tuberculosis Genotype and Drug Resistance in Peru
Background The comparison of Mycobacterium tuberculosis bacterial genotypes with phenotypic, demographic, geospatial and clinical data improves our understanding of how strain lineage influences theExpand
Particles for Improved Cell Expansion
Galway, Ireland Thermoresponsive ELP Particles for Improved Cell Expansion Mariana B Oliveira, Laura Martín,Wenlong Song, Matilde Alonso, J Carlos Rodríguez-Cabello, João F Mano, CorrespondingExpand