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Reactivation of Ocular Dominance Plasticity in the Adult Visual Cortex
In young animals, monocular deprivation leads to an ocular dominance shift, whereas in adults after the critical period there is no such shift. Chondroitin sulphate proteoglycans (CSPGs) areExpand
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BDNF Regulates the Maturation of Inhibition and the Critical Period of Plasticity in Mouse Visual Cortex
Maturation of the visual cortex is influenced by visual experience during an early postnatal period. The factors that regulate such a critical period remain unclear. We examined the maturation andExpand
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Functional postnatal development of the rat primary visual cortex and the role of visual experience: Dark rearing and monocular deprivation
Postnatal development of rat visual cortical functions was studied by recording extracellularly from the primary visual cortex of 22 animals ranging in age from postnatal day 17 (P17) to P45. WeExpand
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The Antidepressant Fluoxetine Restores Plasticity in the Adult Visual Cortex
We investigated whether fluoxetine, a widely prescribed medication for treatment of depression, restores neuronal plasticity in the adult visual system of the rat. We found that chronicExpand
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Environmental enrichment in adulthood promotes amblyopia recovery through a reduction of intracortical inhibition
Loss of visual acuity caused by abnormal visual experience during development (amblyopia) is an untreatable pathology in adults. We report that environmental enrichment in adult amblyopic ratsExpand
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Functional implications of cross-orientation inhibition of cortical visual cells. I. Neurophysiological evidence
Simple and complex cells of striate cortex of anaesthetized and paralysed cats were stimulated with two superimposed one-dimensional grating stimuli of different orientations to investigateExpand
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Requirement of the nicotinic acetylcholine receptor β2 subunit for the anatomical and functional development of the visual system
In the mammalian visual system the formation of eye-specific layers at the thalamic level depends on retinal waves of spontaneous activity, which rely on nicotinic acetylcholine receptor activation.Expand
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The visual physiology of the wild type mouse determined with pattern VEPs
Genetically manipulated mice are important tools for studies on plasticity and degeneration/regeneration in the visual system. However, a description of the basic properties of the visual performanceExpand
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The visual cortex as a spatial frequency analyser.
Abstract Unitary responses to sinusoidal gratings either moving or alternating in phase have been investigated in the optic tract, lateral geniculate body and visual cortex of the cat as a functionExpand
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Structural and functional recovery from early monocular deprivation in adult rats.
Visual deficits caused by abnormal visual experience during development are hard to recover in adult animals. Removal of chondroitin sulfate proteoglycans from the mature extracellular matrix withExpand
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