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Basal plasma growth hormone levels in man: new evidence for rhythmicity of growth hormone secretion.
Circulating GH levels in man fluctuate widely due to pulsatile GH secretion by the pituitary gland. During much of the time, plasma GH is undetectable by current assays. This is punctuated byExpand
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Plasma Growth hormone (GH)-binding proteins: effect on GH binding to receptors and GH action
GH-binding proteins (GH-BP) have recently been discovered in human plasma, but their biological function is unknown. The high affinity GH-BP is related to the GH receptor and may modulate theExpand
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Plasma Growth Hormone (GH)-Binding Proteins: Effect on GH Binding to Receptors and GH Action*
GH-binding proteins (GH-BP) have recently been discovered in human plasma, but their biological function is unknown. The high affinity GH-BP is related to the GH receptor and may modulate theExpand
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Urinary growth hormone excretion rates in normal and acromegalic man: a critical appraisal of its potential clinical utility
The assessment of growth hormone (GH) secretory status is often difficult because of the intermittent nature of GH release and resulting wide swings in plasma GH levels. Urinary GH excretion holdsExpand
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Diurnal pattern of plasma growth hormone-binding protein in man.
The identification of specific GH-binding proteins (GH-BP) in human plasma, one of which is a fragment of the GH receptor, has added new complexity to the state of GH in the circulation. A majorExpand
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Effect of angiotensin-converting enzyme inhibition on pituitary hormone responses to insulin-induced hypoglycemia in humans.
Renin, angiotensin-II, and angiotensin-converting enzyme (ACE) have been found in the hypothalamus and pituitary in rats, and renin, angiotensinogen, and ACE have been found in human pituitaryExpand
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