L. Lyons

Publications226
h-index42
Citations6,811
Highly Influential Citations292
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Comparative anchor tagged sequences (CATS) for integrative mapping of mammalian genomes
TLDR
Using a computer script that automates DNA sequence database alignments, 410 evolutionary conserved primer pair sequences which are specific for anchor locus gene amplification from any mammalian species' DNA are designed.
View on Nature
A genetic linkage map of microsatellites in the domestic cat (Felis catus).
TLDR
A genetic linkage map of microsatellite loci in the feline genome has been constructed including 246 autosomal and 7 X-linked loci, which provides a valuable resource for mapping phenotypic variation in the species and relating it to gene maps of other mammals, including human.
View on PubMed
Feline lymphoma in the post-feline leukemia virus era.
TLDR
A significant decrease in the importance of FeLV-associated types of lymphoma in cats is confirmed and Associations of intestinal lymphoma and inflammatory bowel disease and diet should be further considered.
View on PubMed
Cell biology: A cat cloned by nuclear transplantation
TLDR
The successful cloning of a cat (Felis domesticus) is added to the list of mammals cloned by transfer of a donor cell nucleus into an enucleated ovum.
View on Springer
Birth of African Wildcat cloned kittens born from domestic cats.
TLDR
This study evaluated the in vivo developmental competence, after transfer into domestic cat recipients, of cloned embryos produced by the fusion of African Wildcat fibroblast cell nuclei with domestic cat cytoplasts to represent the first wild carnivores to be produced by nuclear transfer.
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Pathogenesis of feline enteric coronavirus infection
View on SAGE
International equine gene mapping workshop report: a comprehensive linkage map constructed with data from new markers and by merging four mapping resources
TLDR
A comprehensive male linkage map was generated by adding 359 new, informative microsatellites to the International Equine Gene Map half-sibling reference families and by combining genotype data from three independent mapping resources, demonstrating the cohesiveness of the different data sets.
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Feline polycystic kidney disease mutation identified in PKD1.
TLDR
The data suggest that the stop mutation causes feline PKD, providing a test to identify cats that will develop PKD and demonstrating that the domestic cat is an ideal model for human PKD.
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An improved molecular assay for Tritrichomonas foetus.
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Cytidine monophospho-N-acetylneuraminic acid hydroxylase (CMAH) mutations associated with the domestic cat AB blood group
TLDR
Mutations in type B cats likely disrupt the gene function of CMAH, leading to a predominance of NeuAc, the first blood group gene identified outside of non-human primates and humans.
View on Springer
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