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- Publications
- Influence
Norwalk virus: How infectious is it?
- Peter F.M. Teunis, C. Moe, +5 authors R. Calderon
- Biology, Medicine
- Journal of medical virology
- 1 August 2008
Noroviruses are major agents of viral gastroenteritis worldwide. The infectivity of Norwalk virus, the prototype norovirus, has been studied in susceptible human volunteers. A new variant of the hit… Expand
Mechanisms of GII.4 Norovirus Persistence in Human Populations
- L. Lindesmith, Eric Donaldson, +4 authors R. Baric
- Biology, Medicine
- PLoS medicine
- 1 February 2008
Background Noroviruses are the leading cause of viral acute gastroenteritis in humans, noted for causing epidemic outbreaks in communities, the military, cruise ships, hospitals, and assisted living… Expand
Human susceptibility and resistance to Norwalk virus infection
- L. Lindesmith, C. Moe, +6 authors R. Baric
- Biology, Medicine
- Nature Medicine
- 1 May 2003
Infectious diseases have influenced population genetics and the evolution of the structure of the human genome in part by selecting for host susceptibility alleles that modify pathogenesis. Norovirus… Expand
Immunogenetic Mechanisms Driving Norovirus GII.4 Antigenic Variation
- L. Lindesmith, M. Beltramello, +5 authors R. Baric
- Biology, Medicine
- PLoS pathogens
- 1 May 2012
Noroviruses are the principal cause of epidemic gastroenteritis worldwide with GII.4 strains accounting for 80% of infections. The major capsid protein of GII.4 strains is evolving rapidly, resulting… Expand
Norovirus pathogenesis: mechanisms of persistence and immune evasion in human populations
- Eric Donaldson, L. Lindesmith, A. D. Lobue, R. Baric
- Biology, Medicine
- Immunological reviews
- 1 October 2008
Summary: Noroviruses are important human pathogens known to cause epidemic outbreaks of severe gastroenteritis in communities, military barracks, cruise ships, hospitals, and assisted living… Expand
Binding of Norwalk Virus-Like Particles to ABH Histo-Blood Group Antigens Is Blocked by Antisera from Infected Human Volunteers or Experimentally Vaccinated Mice
- P. Harrington, L. Lindesmith, B. Yount, C. Moe, R. Baric
- Biology, Medicine
- Journal of Virology
- 1 December 2002
ABSTRACT Attachment of Norwalk (NV), Snow Mountain (SMV), and Hawaii (HV) virus-like particles (VLPs) to specific ABH histo-blood group antigens was investigated by using human saliva and synthetic… Expand
Viral shape-shifting: norovirus evasion of the human immune system
- Eric Donaldson, L. Lindesmith, A. D. Lobue, R. Baric
- Biology, Medicine
- Nature Reviews Microbiology
- 2 February 2010
Noroviruses are the most common cause of food-borne gastroenteritis worldwide, and explosive outbreaks frequently occur in community settings, where the virus can immobilize large numbers of infected… Expand
Cellular and Humoral Immunity following Snow Mountain Virus Challenge
- L. Lindesmith, C. Moe, J. Lependu, J. Frelinger, J. Treanor, R. Baric
- Biology, Medicine
- Journal of Virology
- 1 March 2005
ABSTRACT Little is known about the immune response to noroviruses. To elucidate the immunobiology of norovirus infection in humans, 15 volunteers were challenged with Snow Mountain virus (SMV), a… Expand
Monoclonal Antibody-Based Antigenic Mapping of Norovirus GII.4-2002
- L. Lindesmith, K. Debbink, +4 authors Eric Donaldson
- Biology, Medicine
- Journal of Virology
- 16 November 2011
ABSTRACT Noroviruses are the primary cause of epidemic gastroenteritis in humans, and GII.4 strains cause ∼80% of the overall disease burden. Surrogate neutralization assays using sera and mouse… Expand
Norovirus Infectivity in Humans and Persistence in Water
- Scot R. Seitz, J. León, +8 authors C. Moe
- Biology, Medicine
- Applied and Environmental Microbiology
- 19 August 2011
ABSTRACT To examine the long-term infectivity of human norovirus in water, 13 study subjects were challenged at different time points with groundwater spiked with the prototype human norovirus,… Expand
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