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Topologically linked protein rings in the bacteriophage HK97 capsid.
- W. R. Wikoff, L. Liljas, R. L. Duda, H. Tsuruta, R. Hendrix, J. Johnson
- Chemistry, BiologyScience
- 22 September 2000
The crystal structure of the double-stranded DNA bacteriophage HK97 mature empty capsid was determined at 3.6 angstrom resolution, creating protein chainmail: topologically linked protein catenanes arranged with icosahedral symmetry.
The refined structure of a protein catenane: the HK97 bacteriophage capsid at 3.44 A resolution.
The three-dimensional structure of the bacterial virus MS2
The structure of the icosahedral bacteriophage MS2 has been determined by X-ray crystallography and the coat protein has no structural similarity to that of any other known RNA virus.
The refined structure of bacteriophage MS2 at 2.8 A resolution.
- R. Golmohammadi, K. Valegård, K. Fridborg, L. Liljas
- ChemistryJournal of molecular biology
- 5 December 1993
The extensive dimer contact supports the idea of dimers as initial building blocks and an assembly pathway is proposed where five dimers converge into a pentamer and 12 pentamers are linked together with free dimers creating a complete particle.
The crystal structure of cricket paralysis virus: the first view of a new virus family
- J. Tate, L. Liljas, P. Scotti, P. Christian, Tianwei Lin, John E. Johnson
- BiologyNature Structural Biology
- 1 August 1999
The genome sequence indicates that the insect picorna-like viruses represent a distinct lineage compared to true picornaviruses, and the capsid structure demonstrates that the two groups are related.
Crystal structure of an RNA bacteriophage coat proteinoperator complex
- K. Valegård, J. Murray, P. Stockley, N. Stonehouse, L. Liljas
- Biology, ChemistryNature
- 13 October 1994
The crystal structure at 3.0 Å resolution of a complex between recombinant MS2 cap-sids and the 19-nucleotide RNA fragment is reported, the first example of a structure at this resolution for a sequence-specific protein-RNA complex apart from the transfer RNA synthetase complexes.
Compensatory adaptation to the deleterious effect of antibiotic resistance in Salmonella typhimurium
The results show that the deleterious effects of a resistance mutation can be compensated by an unexpected variety of mutations.
The 2.8 A structure of a T = 4 animal virus and its implications for membrane translocation of RNA.
Support for this hypothesis is provided by the first atomic resolution structure of a T = 4 RNA virus, where the authors find cleavage sites and helical bundles nearly identical with those observed in T = 3 nodaviruses.
Fitness‐compensatory mutations in rifampicin‐resistant RNA polymerase
Results show that mutations in different components of RNA polymerase are responsible for fitness compensation of a RifR mutant, and some compensatory mutations in rpoB individually caused high‐level resistance.