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Genetic analysis of wound signaling in tomato. Evidence for a dual role of jasmonic acid in defense and female fertility.
Genetic analysis of the wound response pathway in tomato ( Lycopersicon esculentum ) indicates that prosystemin and systemin are upstream components of a defensive signaling cascade that involves… Expand
The synergistic antitumor effect of recombinant interleukin‐1 and low‐dose of cyclophosphamide in tumor‐bearing mice
Intraperitoneal (i. p.) treatment of MOPC104E ascitic tumor‐bearing BALB/c mice with interleukin‐1 (IL‐1) followed by a low dose of cyclophosphamide (CPA) resulted in synergistic prolongation of… Expand
Cyclophosphamide given after active specific immunization augments antitumor immunity by modulation of Th1 commitment of CD4+ T cells
Background and Objectives: In order to evaluate the regulatory effect of cyclophosphamide (CPA) on active specific immunization (ASI)‐induced antitumor immunity, we examined the timing of CPA (100… Expand
A new model of active specific immunotherapy using interleukin‐1 and sonicated tumor supernatant in murine tumor system
The possibility of active specific immunotherapy using interleukin‐1 (IL‐1) plus sonicated tumor supernatant (SS) was examined in a murine tumor model. The growth of intraperitoneally or… Expand
Bone metastasis as a prognostic factor in breast cancer patients with liver metastasis given OK-432-combined adoptive immunotherapy via the hepatic artery
The outcome in 31 patients with liver metastases from breast cancer given OK-432-combined adoptive immunotherapy via the hepatic artery was analyzed. Patients received intraarterial OK-432, a… Expand
Misdiagnosis of primary hepatic marginal zone B cell lymphoma of mucosa-associated lymphoid tissue type, a case report
BackgroundExtra-nodal marginal zone B cell lymphoma of mucosa-associated lymphoid tissue originating in the liver is less common.Case presentationWe described the clinical presentation,… Expand
Analysis of effector cells in tumor-bearing mice pre-treated with active specific immunization followed by cyclophosphamide
In order to analyse the effector population in an immunization model, we treated BALB/c mice with intraperitoneal (i.p.) active specific immunization (ASI), which consists of interleukin (IL)-1-β and… Expand
Sequential immunotherapy using interleukin-1 followed by interleukin-2 of ascitic MOPC104E-bearing mice
This study shows that intraperitoneal injection of interleukin-1 (IL-1), followed by interleukin-2 (IL-2), can effectively eradicate murine ascitic tumor cells. This antitumor effect of IL-1 and IL-2… Expand
[Transarterial immuno-chemotherapy including adoptive transfer of autologous cultured lymphocytes for stage IV breast cancer patients with locally-advanced tumor].
- N. Kan, T. Harada, +6 authors M. Imamura
- Gan to kagaku ryoho. Cancer & chemotherapy
- 1 August 1993
Immuno-chemotherapy via a catheter in the subclavian artery using sequential treatment with OK-432, chemotherapeutic agents (ADM, 5-FU), and cultured autologous lymphocytes, was performed for 9 Stage… Expand