• Publications
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FKBP51 affects cancer cell response to chemotherapy by negatively regulating Akt.
It is shown that FKBP51 acts as a scaffolding protein for Akt and PHLPP and promotes dephosphorylation of Akt, and is downregulated in pancreatic cancer tissue samples and several cancer cell lines. Expand
Persistent Cell Motion in the Absence of External Signals: A Search Strategy for Eukaryotic Cells
Amoeboid behavior is well described by a special kind of random motion: Amoebae show a long persistence time beyond which they start to lose their direction; they move forward in a zig-zag manner; and they make turns every 1–2 min on average. Expand
Identification and characterization of microRNAs in raw milk during different periods of lactation, commercial fluid, and powdered milk products
It is demonstrated for the first time that cow milk contains large amounts of microRNAs (miRNAs) and that the unique expression profile of milk-specific miRNAs can serve as a novel indicator and possible new standard for the quality control of raw milk and milk-related commercial products, such as fluid milk and powdered formula milk. Expand
Nuclear factor high‐mobility group box1 mediating the activation of toll‐like receptor 4 signaling in hepatocytes in the early stage of nonalcoholic fatty liver disease in mice
The notion thatTLR4/MyD88 signaling in liver parenchymal cells plays a pivotal role during the early progression of HFD‐induced NAFLD is supported, in which free HMGB1 served as a positive component mediating TLR4 activation. Expand
Phosphorylation of RasGRP3 on threonine 133 provides a mechanistic link between PKC and Ras signaling systems in B cells.
Light is shed on the proposed "PKC-Ras pathway" and the hypothesis that RasGRP phosphorylation by PKC is a mechanism that integrates DAG signaling systems in T and B cells is supported. Expand
Morphological and molecular evidences for DNA introgression in haploid induction via a high oil inducer CAUHOI in maize
Results suggested that the chromosome elimination was probably responsible for haploid induction in maize, and late somatic elimination might occur. Expand
The role of microRNA expression pattern in human intrahepatic cholangiocarcinoma.
BACKGROUND/AIMS MicroRNAs are a small non-coding family of genes involved in the regulation of gene expression in a post-transcriptional manner and contribute to cell proliferation, differentiationExpand
Characteristics of embB mutations in multidrug-resistant Mycobacterium tuberculosis isolates in Henan, China
  • Dawei Shi, L. Li, +5 authors G. Zhu
  • Biology, Medicine
  • The Journal of antimicrobial chemotherapy
  • 21 July 2011
The results suggest embB mutations alone are not sufficient for the development of full resistance to ethambutol in M. tuberculosis and mutations other than embB are also needed, and confirms the importance of mutations at embB406 and embB497 as hotspots, in addition to embB306, for detecting eth Ambutol resistance. Expand
The protective role of hydrogen-rich saline in experimental liver injury in mice.
HS could protect against liver injury and also inhibit the processes leading to liver cirrhosis and hepatocyte compensatory proliferation, as verified by verifying its protective effects in experimental models of liver injury. Expand
Carrageenan and its applications in drug delivery.
Based on the special characteristics of carrageenan, it has been used as a gelling agent/viscosity enhancing agent for controlled drug release and prolonged retention and for tissue regeneration with therapeutic biomacromolecules and for cell delivery. Expand