Incidence of adverse events and negligence in hospitalized patients. Results of the Harvard Medical Practice Study I.
There is a substantial amount of injury to patients from medical management, and many injuries are the result of substandard care.
Incidence of adverse events and negligence in hospitalized patients.
There is a substantial amount of injury to patients from medical management, and many injuries are the result of substandard care, and the percentage of adverse events attributable to negligence increased in the categories of more severe injuries.
The nature of adverse events in hospitalized patients. Results of the Harvard Medical Practice Study II.
The high proportion that are due to management errors suggests that many others are potentially preventable now, and reducing the incidence of these events will require identifying their causes and developing methods to prevent error or reduce its effects.
The Costs of Adverse Drug Events in Hospitalized Patients
The substantial costs of ADEs to hospitals justify investment in efforts to prevent these events, and estimates of annual costs attributable to all ADEs and preventable ADEs for a 700-bed teaching hospital are $5.6 million and $2.8 million are conservative because they do not include the costs of injuries to patients or malpractice costs.
Pharmacist participation on physician rounds and adverse drug events in the intensive care unit.
The presence of a pharmacist on rounds as a full member of the patient care team in a medical ICU was associated with a substantially lower rate of ADEs caused by prescribing errors.
Relationship between medication errors and adverse drug events
- D. Bates, D. Boyle, M. V. Vliet, James Schneider, L. Leape
- MedicineJournal of general internal medicine
- 1 April 1995
Medication errors are common, although relatively few result in ADEs, however, those that do are preventable, many through physician computer order entry.
Patient participation: current knowledge and applicability to patient safety.
- Y. Longtin, H. Sax, L. Leape, Susan E. Sheridan, L. Donaldson, D. Pittet
- Medicine, Political ScienceMayo Clinic proceedings
A conceptual model including key factors that influence participation and invite patients to contribute to error prevention is proposed, and further research is essential to establish key determinants for the success of patient participation in reducing medical errors and in improving patient safety.
Effect of computerized physician order entry and a team intervention on prevention of serious medication errors.
Physician computer order entry decreased the rate of nonintercepted serious medication errors by more than half, although this decrease was larger for potential ADEs than for errors that actually resulted in an ADE.
Error in medicine.
- L. Leape
- 21 December 1994
Evidence from a number of sources indicates that a substantial number of patients suffer treatment-caused injuries while in the hospital, and inappropriate use of drugs was the leading cause of injuries.
Systems analysis of adverse drug events. ADE Prevention Study Group.
Hospital personnel willingly participated in the detection and investigation of drug use errors and were able to identify underlying systems failures that underlie errors causing adverse drug events and potential ADEs.