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Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale
&NA; Pain intensity is frequently measured on an 11‐point pain intensity numerical rating scale (PI‐NRS), where 0=no pain and 10=worst possible pain. However, it is difficult to interpret theExpand
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Pregabalin for the treatment of postherpetic neuralgia
Objective: To evaluate the efficacy and safety of pregabalin in the treatment of postherpetic neuralgia (PHN). Methods: The authors conducted a multicenter, parallel-group, double-blind,Expand
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Gabapentin for the symptomatic treatment of painful neuropathy in patients with diabetes mellitus: a randomized controlled trial.
CONTEXT Pain is the most disturbing symptom of diabetic peripheral neuropathy. As many as 45% of patients with diabetes mellitus develop peripheral neuropathies. OBJECTIVE To evaluate the effect ofExpand
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Pregabalin for the treatment of painful diabetic peripheral neuropathy: a double-blind, placebo-controlled trial
&NA; A randomized, double‐blind, placebo‐controlled, parallel‐group, multicenter, 8‐week trial (with subsequent open‐label phase) evaluated the effectiveness of pregabalin in alleviating painExpand
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Pregabalin relieves symptoms of painful diabetic neuropathy
Objective: Pregabalin, an alpha2-delta ligand with analgesic, anxiolytic, and anticonvulsant activity, has been evaluated for treatment of neuropathic pain. The authors assessed the efficacy andExpand
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Pregabalin for the treatment of fibromyalgia syndrome: results of a randomized, double-blind, placebo-controlled trial.
OBJECTIVE Fibromyalgia syndrome (FMS) is characterized by widespread musculoskeletal pain and lowered pain threshold. Other prominent symptoms include disordered sleep and fatigue. FMS affects anExpand
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Relief of painful diabetic peripheral neuropathy with pregabalin: a randomized, placebo-controlled trial.
UNLABELLED This was a 6-week, randomized, double-blind, multicenter study evaluating the efficacy of pregabalin in the treatment of painful diabetic neuropathy. Two hundred forty-six men and womenExpand
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Efficacy and safety of pregabalin 600 mg/d for treating painful diabetic peripheral neuropathy: A double-blind placebo-controlled trial
BackgroundRecent consensus guidelines recommend pregabalin as a first-tier treatment for painful diabetic peripheral neuropathy (DPN). We evaluated the efficacy of pregabalin 600 mg/d (300 mg dosedExpand
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Gabapentin as Add‐On Therapy in Children with Refractory Partial Seizures: A 12‐Week, Multicentre, Double‐Blind, Placebo‐Controlled Study
Summary: Purpose: To evaluate the efficacy and safety of gabapentin (Neurontin; GBP) as add‐on therapy for refractory partial seizures in paediatric patients aged 3–12 years.
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Gabapentin in Naive Childhood Absence Epilepsy: Results From Two Double-Blind, Placebo-Controlled, Multicenter Studies
Efficacy and safety of gabapentin monotherapy were evaluated in 33 children with newly diagnosed absence epilepsy in two identical, double-blind, placebo-controlled trials in which a 2-weekExpand
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