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Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale
&NA; Pain intensity is frequently measured on an 11‐point pain intensity numerical rating scale (PI‐NRS), where 0=no pain and 10=worst possible pain. However, it is difficult to interpret the… Expand
Pregabalin for the treatment of postherpetic neuralgia
Objective: To evaluate the efficacy and safety of pregabalin in the treatment of postherpetic neuralgia (PHN). Methods: The authors conducted a multicenter, parallel-group, double-blind,… Expand
Gabapentin for the symptomatic treatment of painful neuropathy in patients with diabetes mellitus: a randomized controlled trial.
CONTEXT Pain is the most disturbing symptom of diabetic peripheral neuropathy. As many as 45% of patients with diabetes mellitus develop peripheral neuropathies. OBJECTIVE To evaluate the effect of… Expand
Pregabalin for the treatment of painful diabetic peripheral neuropathy: a double-blind, placebo-controlled trial
&NA; A randomized, double‐blind, placebo‐controlled, parallel‐group, multicenter, 8‐week trial (with subsequent open‐label phase) evaluated the effectiveness of pregabalin in alleviating pain… Expand
Pregabalin relieves symptoms of painful diabetic neuropathy
Objective: Pregabalin, an alpha2-delta ligand with analgesic, anxiolytic, and anticonvulsant activity, has been evaluated for treatment of neuropathic pain. The authors assessed the efficacy and… Expand
Pregabalin for the treatment of fibromyalgia syndrome: results of a randomized, double-blind, placebo-controlled trial.
OBJECTIVE Fibromyalgia syndrome (FMS) is characterized by widespread musculoskeletal pain and lowered pain threshold. Other prominent symptoms include disordered sleep and fatigue. FMS affects an… Expand
Relief of painful diabetic peripheral neuropathy with pregabalin: a randomized, placebo-controlled trial.
- R. Richter, R. Portenoy, U. Sharma, L. Lamoreaux, H. Bockbrader, L. Knapp
- The journal of pain : official journal of the…
- 1 April 2005
UNLABELLED This was a 6-week, randomized, double-blind, multicenter study evaluating the efficacy of pregabalin in the treatment of painful diabetic neuropathy. Two hundred forty-six men and women… Expand
Efficacy and safety of pregabalin 600 mg/d for treating painful diabetic peripheral neuropathy: A double-blind placebo-controlled trial
BackgroundRecent consensus guidelines recommend pregabalin as a first-tier treatment for painful diabetic peripheral neuropathy (DPN). We evaluated the efficacy of pregabalin 600 mg/d (300 mg dosed… Expand
Gabapentin as Add‐On Therapy in Children with Refractory Partial Seizures: A 12‐Week, Multicentre, Double‐Blind, Placebo‐Controlled Study
Summary: Purpose: To evaluate the efficacy and safety of gabapentin (Neurontin; GBP) as add‐on therapy for refractory partial seizures in paediatric patients aged 3–12 years.
Gabapentin in Naive Childhood Absence Epilepsy: Results From Two Double-Blind, Placebo-Controlled, Multicenter Studies
- V. Trudeau, S. Myers, L. Lamoreaux, H. Anhut, E. Garofalo, J. Ebersole
- Journal of child neurology
- 1 November 1996
Efficacy and safety of gabapentin monotherapy were evaluated in 33 children with newly diagnosed absence epilepsy in two identical, double-blind, placebo-controlled trials in which a 2-week… Expand