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- Publications
- Influence
Recovery of liver function in partially hepatectomized rats evaluated by aminopyrine demethylation capacity
- I. Sendama, B. de Hemptinne, L. Lambotte
- Chemistry, Medicine
- Hepatology
- 1 July 1985
Aminopyrine demethylation was investigated in rats after a 70% hepatectomy to assess possible parallelism between the recovery of mass and function. Tests were performed by analyzing 14CO2 exhalation… Expand
Steatosis is not sufficient to cause an impaired regenerative response after partial hepatectomy in rats.
- C. Picard, L. Lambotte, +4 authors Y. Horsmans
- Biology, Medicine
- Journal of hepatology
- 1 May 2002
BACKGROUND/AIMS
Fatty liver is known to be associated with increased mortality and morbidity after liver resection. The ability of fatty liver to regenerate after two-thirds partial hepatectomy was… Expand
The monoethylglycinexylidide test does not correctly evaluate lidocaine metabolism after ischemic liver injury in the rat
- I. Leclercq, A. Saliez, P. Wallemacq, Y. Horsmans, L. Lambotte
- Medicine
- Hepatology
- 1 November 1997
Although the monoethylglycinexylidide (MEGX) test defined as a single determination of MEGX plasma concentration after lidocaine injection has been proposed as a liver function test, some… Expand
Brain tumor imaging with PET and 2-[carbon-11]thymidine.
- T. Vander Borght, S. Pauwels, +4 authors C. Laterre
- Medicine
- Journal of nuclear medicine : official…
- 1 June 1994
METHODS
To assess the potential of thymidine for imaging brain tumors, 20 patients with untreated (n = 14) and recurrent (n = 6) supratentorial intracranial tumors were studied with PET by using… Expand
DIFFERENTIAL EFFECT OF SWELLING AND ANOXIA ON KIDNEY FUNCTION AND ITS CONSEQUENCES ON THE MECHANISM OF ACTION OF INTRACELLULAR ORGAN PRESERVATION SOLUTIONS
- J. Jamart, L. Lambotte
- Medicine
- Transplantation
- 1 October 1982
In order to differentiate the effects of swelling and anoxia on kidney function, a canine experimental model is used. After complete liberation of kidneys and their vessels from adjacent tissues,… Expand
Production of [2-11C]thymidine for quantification of cellular proliferation with PET.
- T. Vander Borght, D. Labar, S. Pauwels, L. Lambotte
- Chemistry, Medicine
- International journal of radiation applications…
- 1991
A three-step synthesis of [2-11C]thymidine, using [11C]urea as precursor, is described. [2-11C]Thymine was obtained by cyclization of [11C]urea and diethyl beta-methylmalate in fuming sulfuric acid.… Expand
The compensatory hyperplasia (liver regeneration) following ligation of a portal branch is initiated before the atrophy of the deprived lobes.
- L. Lambotte, B. Li, I. Leclercq, C. Sempoux, A. Saliez, Y. Horsmans
- Biology, Medicine
- Journal of hepatology
- 1 June 2000
BACKGROUND/AIMS
In rats, partial ligation of portal branches produces atrophy of the deprived lobes and hypertrophy of the intact lobes. The hepatocyte proliferation observed in the nondeprived lobes… Expand
Saccharomyces boulardii upgrades cellular adaptation after proximal enterectomy in rats
- J. Buts, N. de Keyser, +6 authors P. Tulkens
- Biology, Medicine
- Gut
- 1 July 1999
BACKGROUND Saccharomyces boulardii is a non-pathogenic yeast which exerts trophic effects on human and rat small intestinal mucosa. AIMS To examine the effects of S boulardii on ileal adaptation… Expand
Retrorsine: a kinetic study of its influence on rat liver regeneration in the portal branch ligation model.
- C. Picard, L. Lambotte, +5 authors Y. Horsmans
- Biology, Medicine
- Journal of hepatology
- 1 July 2003
BACKGROUND
Retrorsine, a naturally occurring pyrrolizidine alkaloid, impairs liver regeneration after partial hepatectomy by mechanisms that are still unclear.
AIM
The aim of the study was to… Expand
Noninvasive measurement of liver regeneration with positron emission tomography and [2-11C]thymidine.
- T. Vander Borght, L. Lambotte, S. Pauwels, D. Labar, C. Beckers, C. Dive
- Chemistry, Medicine
- Gastroenterology
- 1 September 1991
The feasibility of liver regeneration determination with [2-11C]thymidine and positron emission tomography was investigated in partially hepatectomized rats. Serial tomographic scans were performed… Expand
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