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Cancer stem cells in solid tumors: an overview and new approaches for their isolation and characterization
- V. Tirino, V. Desiderio, G. Papaccio
- BiologyFASEB journal : official publication of the…
- 1 January 2013
An overview of the main characteristics and approaches used to identify, isolate, and characterize cancer stem cells from solid tumors is provided.
Human mandible bone defect repair by the grafting of dental pulp stem/progenitor cells and collagen sponge biocomplexes.
It is demonstrated that a DPC/collagen sponge biocomplex can completely restore human mandible bone defects and indicates that this cell population could be used for the repair and/or regeneration of tissues and organs.
Histone Deacetylase Inhibition with Valproic Acid Downregulates Osteocalcin Gene Expression in Human Dental Pulp Stem Cells and Osteoblasts: Evidence for HDAC2 Involvement
It is concluded that VPA does not induce terminal differentiation of osteoblasts, but stimulates the generation of less mature cells, and specific suppression of an individual HDAC by RNA interference could enhance only a single aspect of osteoblast differentiation, and thus produce selective effects.
Biological and therapeutic activities, and anticancer properties of curcumin.
All the studies reviewed herein suggest that curcumin is able to exert anti-inflammatory, antiplatelet, antioxidative, hepatoprotective and antitumor activities, particularly against cancers of the liver, skin, pancreas, prostate, ovary, lung and head neck, as well as having a positive effect in the treatment of arthritis.
Three Years After Transplants in Human Mandibles, Histological and In‐Line Holotomography Revealed That Stem Cells Regenerated a Compact Rather Than a Spongy Bone: Biological and Clinical Implications
Although the bone regenerated at the graft sites is not of the proper type found in the mandible, it does seem to have a positive clinical impact and creates steadier mandibles, may well increase implant stability, and, additionally, may improve resistance to mechanical, physical, chemical, and pharmacological agents.
Postextraction Dental Implant in the Aesthetic Zone, Socket Shield Technique Versus Conventional Protocol
The socket shield technique seems to be a safe surgical technique that allows an implant rehabilitation characterized by better aesthetic outcomes, and shows better values of both marginal bone level and pink aesthetic score.
Human dental pulp stem cells: from biology to clinical applications.
- R. d’Aquino, A. De Rosa, G. Papaccio
- Biology, MedicineJournal of experimental zoology. Part B…
- 15 July 2009
Results enforce the notion that DPSCs can be used successfully for tissue engineering and show good adherence and bone tissue formation on microconcavity surface textures.
Porcine-derived xenograft combined with a soft cortical membrane versus extraction alone for implant site development: a clinical study in humans.
- V. Festa, F. Addabbo, L. Laino, F. Femiano, R. Rullo
- MedicineClinical implant dentistry and related research
- 14 November 2011
The placement of a porcine xenograft with a membrane in an extraction socket can be used to reduce the hard tissue reabsorption after tooth extraction compared with extraction-alone sites.
Prognostic significance of N-Cadherin expression in oral squamous cell carcinoma.
The key-role of N-Cadherin in oral carcinogenesis and in the prognostic stratification of patients is underlined, with significant a statistical trend for stage and a correlation with worst patient outcome observed.