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A systematic review and meta-analysis of the psychosis continuum: evidence for a psychosis proneness–persistence–impairment model of psychotic disorder
TLDR
There is evidence, however, that transitory developmental expression of psychosis (psychosis proneness) may become abnormally persistent and subsequently clinically relevant (impairment), depending on the degree of environmental risk the person is additionally exposed to. Expand
The relationship between neurocognition and social cognition with functional outcomes in schizophrenia: A meta-analysis
TLDR
Overall, social cognition was more strongly associated with community functioning than neurocognition, with the strongest associations being between theory of mind and functional outcomes. Expand
Genome-wide association study identifies five new schizophrenia loci
TLDR
The role of common genetic variation in schizophrenia in a genome-wide association study of substantial size is examined, suggesting MIR137-mediated dysregulation as a previously unknown etiologic mechanism in schizophrenia. Expand
Prospective cohort study of cannabis use, predisposition for psychosis, and psychotic symptoms in young people
TLDR
Cannabis use moderately increases the risk of psychotic symptoms in young people but has a much stronger effect in those with evidence of predisposition for psychosis. Expand
Meta-analyses of cognitive functioning in euthymic bipolar patients and their first-degree relatives
TLDR
Executive function and verbal memory are candidate bipolar endophenotypes given large deficits in these domains in bipolar patients and small, but intermediate, cognitive impairments in first-degree relatives. Expand
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
TLDR
Empirical evidence of shared genetic etiology for psychiatric disorders can inform nosology and encourages the investigation of common pathophysiologies for related disorders. Expand
Validity and reliability of the CAPE: a self‐report instrument for the measurement of psychotic experiences in the general population
TLDR
This study tested the reliability and validity of the Community Assessment of Psychic Experiences (CAPE42) and demonstrated the prognostic validity of self‐reported psychotic experiences. Expand
Childhood abuse as a risk factor for psychotic experiences
TLDR
It is suggested that early childhood trauma increases the risk for positive psychotic symptoms, and fits well with recent models that suggest that early adversities may lead to psychological and biological changes that increase psychosis vulnerability. Expand
Childhood abuse as a risk factor for psychotic experiences
Objective: To examine the hypothesis that individuals from the general population who report childhood abuse are at increased risk of developing positive psychotic symptoms.
Alterations in theory of mind in patients with schizophrenia and non‐psychotic relatives
TLDR
The present study examined whether alterations in theory of mind reflect a trait that can be detected in non‐psychotic relatives of patients with schizophrenia. Expand
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