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Reversal of multidrug resistance by co-delivery of paclitaxel and lonidamine using a TPGS and hyaluronic acid dual-functionalized liposome for cancer treatment.
TLDR
It is suggested that this dual-functional liposome for co-delivery of a cytotoxic drug and an MDR modulator provides a promising strategy for reversal of MDR in cancer treatment. Expand
Danggui-Shaoyao-San ameliorates cognition deficits and attenuates oxidative stress-related neuronal apoptosis in d-galactose-induced senescent mice.
TLDR
It is demonstrated that DE has neuroprotective effects in d-gal-induced senescent mice by ameliorating oxidative stress induced neuronal apoptosis in the brain. Expand
Four new steroidal glycosides from Solanum torvum and their cytotoxic activities
TLDR
Two novel C-22 steroidal lactone saponins, namely solanolactosides A, B and two new spirostanol glycosides, namely torvosides M, N (3, 4) were isolated from ethanol extract of aerial parts of Solanum torvum and showed significant cytotoxic activity with the cell lines. Expand
(+/-)-Praeruptorin A enantiomers exert distinct relaxant effects on isolated rat aorta rings dependent on endothelium and nitric oxide synthesis.
TLDR
Findings indicated that (+)-praeruptorin A and (-)-praiseful A exerted distinct relaxant effects on isolated rat aorta rings, which might be mainly attributed to nitric oxide synthesis catalyzed by endotric oxide synthase. Expand
Preparative isolation and purification of coumarins from Cnidium monnieri (L.) Cusson by high-speed counter-current chromatography.
A high-speed counter-current chromatography (HSCCC) method for separation and purification of coumarins from Cnidium monnieri (L.) Cusson was developed by using stepwise elution with a pair ofExpand
Neutrophil-mediated anticancer drug delivery for suppression of postoperative malignant glioma recurrence.
TLDR
It is shown that NEs carrying liposomes that contain paclitaxel (PTX) can penetrate the brain and suppress the recurrence of glioma in mice whose tumour has been resected surgically, and this NE-mediated delivery of drugs efficiently slows the recurrent growth of tumours. Expand
¹H NMR-based metabolomics approach to evaluate the effect of Xue-Fu-Zhu-Yu decoction on hyperlipidemia rats induced by high-fat diet.
TLDR
The combined results demonstrated that XFZYD could ameliorate the hyperlipidemic symptoms in a global scale and restore the abnormal metabolic state to a near normal level in a time-dependent pattern. Expand
Simultaneous determination of nine saponins from Panax notoginseng using HPLC and pressurized liquid extraction.
TLDR
The developed HPLC and PLE is an effective approach for simultaneously quantitative determination of sapoinins in P. notoginseng, which would be valuable on standardization of sample preparation for quality control of Chinese medicines. Expand
Preparative isolation and purification of psoralen and isopsoralen from Psoralea corylifolia by high-speed counter-current chromatography.
TLDR
Psoralen and isopsoralen were separated from Psoralea corylifolia by high-speed counter-current chromatography using a two-phase solvent system and identified with 1H NMR and 13C NMR. Expand
Preparative isolation and purification of three flavonoids from the Chinese medicinal plant Epimedium koreamum Nakai by high-speed counter-current chromatography.
A preparative high-speed counter-current chromatography (HSCCC) method for isolation and purification of flavonoids from the Chinese medicinal plant Epimedium koreamum Nakai was successfullyExpand
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