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Human internal and external exposure to PBDEs--a review of levels and sources.
This paper reviews the existing literature on human exposure to polybrominated diphenyl ethers (PBDEs), with particular focus on external exposure routes (e.g. dust, diet, and air) and the resultingExpand
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Polybrominated diphenyl ethers in paired samples of maternal and umbilical cord blood plasma and associations with house dust in a Danish cohort.
Brominated flame retardants (BFRs), in particular the polybrominated diphenyl ethers (PBDEs), have been used in consumer products for many years to increase fire resistance. Recently, developmentalExpand
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The comet assay as a rapid test in biomonitoring occupational exposure to DNA-damaging agents and effect of confounding factors.
Within the last decade, the comet assay has been used with increasing popularity to investigate the level of DNA damage in terms of strand breaks and alkaline labile sites in biomonitoring studies.Expand
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Optimization of chemically defined cell culture media--replacing fetal bovine serum in mammalian in vitro methods.
Quality assurance is becoming increasingly important. Good laboratory practice (GLP) and good manufacturing practice (GMP) are now established standards. The biomedical field aims at an increasingExpand
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Urinary 1-hydroxypyrene (1-HP) in environmental and occupational studies--a review.
A total of 132 studies were identified, of which 25 studies addressed environmental exposure to polycyclic aromatic hydrocarbons (PAHs) in the general population. Of these 9 studies includedExpand
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Urinary excretion of phthalate metabolites, phenols and parabens in rural and urban Danish mother-child pairs.
Some phthalates, parabens and phenols have shown adverse endocrine disrupting effects in animal studies and are also suspected to be involved in human reproductive problems. However, knowledge aboutExpand
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Cancer risk in humans predicted by increased levels of chromosomal aberrations in lymphocytes: Nordic study group on the health risk of chromosome damage.
Cytogenetic assays in peripheral blood lymphocytes (PBL) have been used extensively to survey the exposure of humans to genotoxic agents. The conceptual basis for this has been the hypothesis thatExpand
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Chromosomal aberrations and SCEs as biomarkers of cancer risk.
Previous studies have suggested that the frequency of chromosomal aberrations (CAs), but not of sister chromatid exchanges (SCEs), predicts cancer risk. We have further examined this relationship inExpand
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Impact of Types of Lymphocyte Chromosomal Aberrations on Human Cancer Risk
The frequency of cells with structural chromosomal aberrations (CAs) in peripheral blood lymphocytes is the first genotoxicity biomarker that has shown an association with cancer risk. CAs areExpand
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Personal Exposure to Ultrafine Particles and Oxidative DNA Damage
Exposure to ultrafine particles (UFPs) from vehicle exhaust has been related to risk of cardiovascular and pulmonary disease and cancer, even though exposure assessment is difficult. We studiedExpand
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