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Light Adaptation through Phosphoinositide-Regulated Translocation of Drosophila Visual Arrestin
Photoreceptor cells adapt to bright or continuous light, although the molecular mechanisms underlying this phenomenon are incompletely understood. Here, we report a mechanism of light adaptation inExpand
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Molecular mechanism for the regulation of human ACC2 through phosphorylation by AMPK.
Acetyl-CoA carboxylases (ACCs) have been highlighted as therapeutic targets for obesity and diabetes, as they play crucial roles in fatty acid metabolism. ACC activity is regulated through theExpand
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MiR-125a promotes paclitaxel sensitivity in cervical cancer through altering STAT3 expression
Cervical cancer (CC) is one of the most common malignancies in women. Paclitaxel is the front-line chemotherapeutic agent for treating CC. However, its therapeutic efficacy is limited because ofExpand
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Crystal structure of Clostridium thermocellum ribose-5-phosphate isomerase B reveals properties critical for fast enzyme kinetics
Ribose-5-phosphate isomerase (Rpi) catalyzes the conversion of d-ribose 5-phosphate (R5P) to d-ribulose 5-phosphate, which is an important step in the non-oxidative pathway of the pentose phosphateExpand
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Crystal structure of Pfu, the high fidelity DNA polymerase from Pyrococcus furiosus.
We have determined a 2.6A resolution crystal structure of Pfu DNA polymerase, the most commonly used high fidelity PCR enzyme, from Pyrococcus furiosus. Although the structures of Pfu and KOD1 areExpand
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Characterization of a recombinant cellobiose 2-epimerase from Dictyoglomus turgidum that epimerizes and isomerizes β-1,4- and α-1,4-gluco-oligosaccharides
A recombinant putative N-acyl-d-glucosamine 2-epimerase from Dictyoglomus turgidum was identified as a cellobiose 2-epimerase by evaluating its substrate specificity. The purified enzyme was a 46 kDaExpand
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Educational Effectiveness, Target, and Content for Prudent Antibiotic Use
Widespread antimicrobial use and concomitant resistance have led to a significant threat to public health. Because inappropriate use and overuse of antibiotics based on insufficient knowledge are oneExpand
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Current use of autologous adipose tissue-derived stromal vascular fraction cells for orthopedic applications
Autologous adipose stromal vascular fractions (SVFs) containing adipose tissue-derived stem cells (ASCs) are currently being used in clinical settings for various orthopedic applications for humanExpand
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Ribosomal protein S3 is phosphorylated by Cdk1/cdc2 during G2/M phase.
Ribosomal protein S3 (rpS3) is a multifunctional protein involved in translation, DNA repair, and apoptosis. The relationship between rpS3 and cyclin-dependent kinases (Cdks) involved in cell cycleExpand
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A Collaborative Virtual Reality Environment for Molecular Biology
A collaborative virtual reality environment (CRVE) can be used in molecular biology because it can provide users with virtual experiences of three dimensional molecular models in cyberspaces. Expand
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