• Publications
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Ca, Mg-ATPase activity of permeabilised rat heart cells and its functional coupling to oxidative phosphorylation of the cells.
  • L. Kümmel
  • Chemistry, Medicine
  • Cardiovascular research
  • 1 May 1988
TLDR
Isolated rat heart cells permeabilised by digitonin were examined as an experimental model to study heart bioenergetics and appeared to be functionally coupled with Oxidative phosphorylation and the ATPase activity of the cells. Expand
The rat fructose-1,6-bisphosphatase gene. Structure and regulation of expression.
TLDR
The accumulation of fructose-1,6-bisphosphatase mRNA in hepatocytes incubated with cAMP suggests that the gene may be cAMP-responsive, which is consistent with the presence of three consensus cAMP regulatory elements at positions -169, -282, and -698 in the 5'-flanking region of the gene. Expand
Estimation of Pathways of Glucose Metabolism Employing [14C] Glucose
  • L. Kümmel
  • Chemistry, Medicine
  • Zeitschrift fur Naturforschung. Teil C: Biochemie…
  • 1973
TLDR
It has been found that the ratio of both pathways changes with time of incubation, and the dependence of the contribution of the pentose cycle to glucose metabolism on the length of incubations may be related to the possible changes of erythrocyte ATP content during the separation and washing of these cells. Expand
Evidence for possible interrelationship between gluconeogenesis and ketogenesis?
  • L. Kümmel
  • Chemistry, Medicine
  • Biochemistry international
  • 1 March 1984
TLDR
It is proposed that, in intact liver cells, pyruvate is transported into mitochondria in exchange for intramitochondrially generated acetoacetate, and that the mechanism proposed may be of physiological importance. Expand
Mitochondrial pyruvate carrier—A possible link between gluconeogenesis and ketogenesis in the liver
  • L. Kümmel
  • Chemistry, Medicine
  • Bioscience reports
  • 1 July 1987
TLDR
The results suggest that, in intact liver cells, cytoplasmic pyruvate is transported into mitochondria in exchange for intramitochondrially generated acetoacetate, suggesting an interrelationship between gluconeogenesis and ketogenesis may exist in the liver at the level of mitochondrial pyruVate carrier. Expand
Mutual additivity of hormonal and non-hormonal stimulation of gluconeogenesis.
  • L. Kümmel
  • Chemistry, Medicine
  • Biochemistry international
  • 1 May 1987
TLDR
Simultaneous administration of alpha-adrenergic agents with oleate or acetate increased gluconeogenesis by 110% and 90-100%, respectively, thus documenting mutual additivity of hormonal and non-hormonal stimulation; propranolol did not affect the mutualAdditivity of the effects observed. Expand
Possible interrelationship between gluconeogenesis and ketogenesis in the liver
  • L. Kümmel
  • Chemistry, Medicine
  • Bioscience reports
  • 1 July 1983
TLDR
The results suggest that, in intact liver cells, pyruvate is transported into mitochondria in exchange for acetoacetate and that an interrelationship between gluconeogenesis and ketogenesis at the level of mitochondrial pyruVate carrier may exist in the liver. Expand
Isolated permeabilized rat heart cells as a model to study heart bioenergetics in situ.
  • L. Kümmel
  • Chemistry, Medicine
  • Acta Universitatis Carolinae. Medica
  • 1989
TLDR
Isolated rat heart cells permeabilized by digitonin were examined as an experimental model to study heart bioenergetics and ATPase activity appeared to be functionally coupled to oxidative phosphorylation of the cells. Expand
Human heart aneurysm: biochemical and morphological characteristics.
TLDR
The highest activity of the pentose-phosphate shunt, together with the highest rate of proteosynthesis, was observed in the sample from the left ventricular wall aneurysm with marked inflammatory infiltration of the tissue. Expand
Device and method for joining webs.
Device (100) for connecting strips to form an endless strip with a clamping device (110, 120) with a clamping device on the inlet side (110-r, 20-r) and a clamp output side ( 110-l, 12O-l), a cuttingExpand
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