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Effect of Losartan, an Angiotensin II Antagonist, on Hepatic Fibrosis Induced by CCl4 in Rats
TLDR
Losartan significantly inhibited the progression of hepatic fibrosis induced by CCl4, and the inhibitory effect of losartan on hepatic Fibrosis might be associated with its ability to inhibit the production of TNF-α and TGF-β 1 by activated KCs. Expand
The molecular and electrophysiological mechanism of Buyanghuanwu Decoction in learning and memory ability of vascular dementia rats
TLDR
It is suggested that increased ERK2 and CaMKIIIy due to BYHWD may partially account for its effect of neuroprotection standing against ischemic injury in the hippocampal CA1 region. Expand
First report of an epidemic of diarrhoea in human neonates involving the new rotavirus and biological characteristics of the epidemic virus strain (KMB/R85)
TLDR
It was found that KMB/R85 strain did not possess the common group antigen shared by group A rotaviruses and was antigenically similar to the Chinese adult diarrhoea rotavirus (serogroup B). Expand
Population pharmacokinetics study of cyclosporine A in renal transplantation patients
TLDR
The PPK final model of oral CsA in renal transplant patients can be established using the NONMEM software, which offers reference for the individualized use of Cs a in clinical practice. Expand
The influence of 5,7,3'-triacetyl hesperetin on Jak2/Stat3 signalling pathway and related apoptosis proteins of fibroblast-like synoviocytes in rats with adjuvant arthritis
TLDR
TAHP can inhibit the proliferation of FLS in a dose-and-time dependent manner and might be associated with inhibiting Jak2/Stat3 signalling pathway, promoting the expressions of Bax and Caspase-3, and decreasing the expression of Bcl-2. Expand
HFE Mutation and Dietary Iron Content Interact to Increase Ischemia/Reperfusion Injury of the Heart in Mice
TLDR
It is suggested that increased amount of ROS and reduced antioxidant reserve secondary to iron overloading may be instrumental for the susceptibility of the HFE gene knockout mice to cardiac injury. Expand
Effect of salvianolic acid A and C compatibility on inflammatory cytokines in rats with unilateral ureteral obstruction
TLDR
Salvianolic acid A and C are component molecules of drug compatibility, and they may protect renal function and improve tubular function and renal pathology to a certain degree in UUO, and this improvement may be related to a reduction in inflammatory cytokines CCL5 and CXCL10 secretion in the U UO rat kidney. Expand
Effects of integrative Chinese and Western medicine on arterial oxygen saturation in patients with severe acute respiratory syndrome
TLDR
ICWM treatment, particularly when it is used for intervention in the early stage, is beneficial for maintaining normal SaO2 in SARS patients. Expand
Serum bilirubin and the risk of rheumatoid arthritis
TLDR
Increased evidence shows that bilirubin should be a protective factor for autoimmune disease, however, the relationship between bilirUBin and RA remain unclear. Expand
CLINICAL EFFECT OF JITAI TABLET COMBINED WITH LOFEXIDINE IN THE TREATMENT OF HEROIN DEPENDENCE
TLDR
Jitai tablet combined with lofexidine can treat heroin dependence effectively with fewer adverse effects and it is fairly cheaper. Expand
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