• Publications
  • Influence
The Eurasian Heartland: A continental perspective on Y-chromosome diversity
The nonrecombining portion of the human Y chromosome has proven to be a valuable tool for the study of population history. The maintenance of extended haplotypes characteristic of particularExpand
  • 451
  • 39
  • PDF
A pre-Columbian Y chromosome-specific transition and its implications for human evolutionary history.
A polymorphic C-->T transition located on the human Y chromosome was found by the systematic comparative sequencing of Y-specific sequence-tagged sites by denaturing high-performance liquidExpand
  • 364
  • 32
  • PDF
Chronic inhibition of glutamate uptake produces a model of slow neurotoxicity.
Defects in neurotransmitter glutamate transport may be an important component of chronic neurotoxicity in diseases such as amyotrophic lateral sclerosis. There are no reliable models of slowExpand
  • 613
  • 27
  • PDF
Genetic relationship of populations in China.
  • J. Chu, W. Huang, +11 authors L. Jin
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 29 September 1998
Despite the fact that the continuity of morphology of fossil specimens of modern humans found in China has repeatedly challenged the Out-of-Africa hypothesis, Chinese populations are underrepresentedExpand
  • 339
  • 26
  • PDF
Mammalian Bax-induced plant cell death can be down-regulated by overexpression of Arabidopsis Bax Inhibitor-1 (AtBI-1)
We recently isolated the AtBI-1 (Arabidopsis Bax Inhibitor-1) gene, the expression of which suppressed Bax-induced cell death in yeast. To determine whether the same is true in the plant system,Expand
  • 229
  • 18
  • PDF
Worldwide DNA sequence variation in a 10-kilobase noncoding region on human chromosome 22.
  • Z. Zhao, L. Jin, +10 authors W. Li
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 10 October 2000
Human DNA sequence variation data are useful for studying the origin, evolution, and demographic history of modern humans and the mechanisms of maintenance of genetic variability in humanExpand
  • 150
  • 17
  • PDF
Identification of mouse SLC39A8 as the transporter responsible for cadmium-induced toxicity in the testis.
  • T. Dalton, L. He, +6 authors D. Nebert
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 1 March 2005
Testicular necrosis is a sensitive endpoint for cadmium (Cd(2+), Cd) toxicity across all species tested. Resistance to Cd-induced testicular damage is a recessive trait assigned to the Cdm locus onExpand
  • 229
  • 12
Polynesian origins: insights from the Y chromosome.
  • B. Su, L. Jin, +8 authors R. Deka
  • Geography, Medicine
  • Proceedings of the National Academy of Sciences…
  • 18 July 2000
The question surrounding the colonization of Polynesia has remained controversial. Two hypotheses, one postulating Taiwan as the putative homeland and the other asserting a Melanesian origin of theExpand
  • 158
  • 11
  • PDF
Genetic dating indicates that the Asian–Papuan admixture through Eastern Indonesia corresponds to the Austronesian expansion
Although the Austronesian expansion had a major impact on the languages of Island Southeast Asia, controversy still exists over the genetic impact of this expansion. The coexistence of both Asian andExpand
  • 76
  • 8
  • PDF
Mutation rate varies among alleles at a microsatellite locus: phylogenetic evidence.
The understanding of the mutational mechanism that generates high levels of variation at microsatellite loci lags far behind the application of these genetic markers. A phylogenetic approach wasExpand
  • 164
  • 6