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Epidemiology and outcomes of osteoporotic fractures
Bone mass declines and the risk of fractures increases as people age, especially as women pass through the menopause. Hip fractures, the most serious outcome of osteoporosis, are becoming more… Expand
Hip fractures in the elderly: A world-wide projection
Hip fractures are recognized to be a major public health problem in many Western nations, most notably those in North America, Europe and Oceania. Incidence rates for hip fracture in other parts of… Expand
History of the Rochester Epidemiology Project.
- L. J. Melton
- Mayo Clinic proceedings
- 1 March 1996
The Rochester Epidemiology Project is a unique medical records-linkage system that encompasses the care delivered to residents of Rochester and Olmsted County, Minnesota. It is the creation of Dr.… Expand
Sex steroids and the construction and conservation of the adult skeleton.
Here we review and extend a new unitary model for the pathophysiology of involutional osteoporosis that identifies estrogen (E) as the key hormone for maintaining bone mass and E deficiency as the… Expand
Risk factors for deep vein thrombosis and pulmonary embolism: a population-based case-control study.
- J. Heit, M. Silverstein, D. Mohr, T. Petterson, W. O'fallon, L. J. Melton
- Archives of internal medicine
- 27 March 2000
BACKGROUND Reported risk factors for venous thromboembolism (VTE) vary widely, and the magnitude and independence of each are uncertain. OBJECTIVES To identify independent risk factors for deep… Expand
Trends in the incidence of deep vein thrombosis and pulmonary embolism: a 25-year population-based study.
- M. Silverstein, J. Heit, D. Mohr, T. Petterson, W. O'fallon, L. J. Melton
- Archives of internal medicine
- 23 March 1998
BACKGROUND The incidence of venous thromboembolism has not been well described, and there are no studies of long-term trends in the incidence of venous thromboembolism. OBJECTIVES To estimate the… Expand
Prevalence of monoclonal gammopathy of undetermined significance.
- R. Kyle, T. Therneau, +6 authors L. J. Melton
- The New England journal of medicine
- 30 March 2006
BACKGROUND The prevalence of monoclonal gammopathy of undetermined significance (MGUS), a premalignant plasma-cell disorder, among persons 50 years of age or older has not been accurately determined.… Expand
The use of clinical risk factors enhances the performance of BMD in the prediction of hip and osteoporotic fractures in men and women
SummaryBMD and clinical risk factors predict hip and other osteoporotic fractures. The combination of clinical risk factors and BMD provide higher specificity and sensitivity than either… Expand
Medical Expenditures for the Treatment of Osteoporotic Fractures in the United States in 1995: Report from the National Osteoporosis Foundation
- N. F. Ray, J. K. Chan, M. Thamer, L. J. Melton
- Journal of bone and mineral research : the…
- 1 January 1997
Osteoporotic fractures are a significant public health problem, resulting in substantial morbidity and mortality. Previous estimates of the economic burden of osteoporosis, however, have not fully… Expand
Prevalence and clinical spectrum of gastroesophageal reflux: a population-based study in Olmsted County, Minnesota.
BACKGROUND & AIMS Gastroesophageal reflux is considered a common condition, but detailed population-based data on reflux in the United States are lacking. The aim of this study was to determine the… Expand