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Immunological disorders in C virus chronic active hepatitis: A prospective case‐control study
TLDR
The prevalences of cryoglobulinemia, rheumatoid factor and antitissue antibodies were significantly higher than those in the control group and patients with chronic hepatitis B, and can be classified into several categories.
Human Serum Facilitates Hepatitis C Virus Infection, and Neutralizing Responses Inversely Correlate with Viral Replication Kinetics at the Acute Phase of Hepatitis C Virus Infection
TLDR
Using a sensitive neutralization assay based on infectious HCV pseudoparticles, the kinetics of humoral responses in a cohort of acute-phase patients infected during a single nosocomial outbreak in a hemodialysis center are studied to provide new insights into the mechanisms of viral persistence and immune control of viremia.
Extrahepatic Immunologic Manifestations in Chronic Hepatitis C and Hepatitis C Virus Serotypes
TLDR
A serotyping assay was used to study whether the occurrence of extrahepatic immunologic abnormalities in patients with chronic hepatitis C is serotype dependent, and several studies indicate that particular HCV genotypes are associated with more severe liver disease and poorer response to interferon- therapy.
High-Dose Immunoglobulin Therapy for Severe IgA Nephropathy and Henoch-Schonlein Purpura
TLDR
High-dose intravenous immunoglobulins are effective in some human immune-mediated diseases and are postulated to favor viral and bacterial infections, a known trigger of flare-ups in these diseases, or activate noxious isotypic compensatory mechanisms in patients with severe IgAN and HSP who had indicators of poor prognosis.
Plasma cytokine and soluble receptor signature predicts outcome of patients with classical Hodgkin's lymphoma: a study from the Groupe d'Etude des Lymphomes de l'Adulte.
TLDR
Plasma cytokine signature is sufficient to predict disease-related outcome in classical Hodgkin's lymphoma, and allows the identification of patients with very high risk of treatment failure, adding significant prognostic information to its predictive power.
Antiphospholipid antibodies in adults with immune thrombocytopenic purpura
TLDR
The significant associations between thrombosis and LA or high IgG‐aCL level or high aCL level suggest that aPL should be tested at ITP diagnosis.
Long lasting IgG subclass and antibacterial polysaccharide antibody deficiency after allogeneic bone marrow transplantation.
TLDR
Most patients with Hib pneumonia showed virtually no IgG antibody response to Hib, and one-half of the patients had a moderate IgM and IgA response; however, the abnormalities are not clearly predictive of infections in individual cases.
Inflammatory response to cardiopulmonary bypass using roller or centrifugal pumps.
TLDR
During the operation, CFP caused greater complement and neutrophil activation, and after theoperation, the inflammatory response was similar using either roller pump or CFP.
Overproduction of proinflammatory cytokines imbalanced by their antagonists in POEMS syndrome.
TLDR
The results suggest that the manifestations of POEMS syndrome might be regarded as the result of a marked activation of the proinflammatory cytokine network associated with a weak or even decreased (TGF beta 1) antagonistic reaction insufficient to counteract the noxious effects of cytokines.
Immunogenicity of Haemophilus influenzae type b conjugate vaccine in allogeneic bone marrow recipients.
TLDR
Hib-CPS-T is more immunogenic than Hib-C PS in marrow recipients, and induced a response in IgG2-deficient patients whereas Hib- CPS alone did not.
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