Immunological disorders in C virus chronic active hepatitis: A prospective case‐control study
The prevalences of cryoglobulinemia, rheumatoid factor and antitissue antibodies were significantly higher than those in the control group and patients with chronic hepatitis B, and can be classified into several categories.
Extrahepatic Immunologic Manifestations in Chronic Hepatitis C and Hepatitis C Virus Serotypes
- J. Pawlotsky, F. Roudot-thoraval, D. Dhumeaux
- Medicine, BiologyAnnals of Internal Medicine
- 1 February 1995
A serotyping assay was used to study whether the occurrence of extrahepatic immunologic abnormalities in patients with chronic hepatitis C is serotype dependent, and several studies indicate that particular HCV genotypes are associated with more severe liver disease and poorer response to interferon- therapy.
Human Serum Facilitates Hepatitis C Virus Infection, and Neutralizing Responses Inversely Correlate with Viral Replication Kinetics at the Acute Phase of Hepatitis C Virus Infection
Using a sensitive neutralization assay based on infectious HCV pseudoparticles, the kinetics of humoral responses in a cohort of acute-phase patients infected during a single nosocomial outbreak in a hemodialysis center are studied to provide new insights into the mechanisms of viral persistence and immune control of viremia.
Plasma cytokine and soluble receptor signature predicts outcome of patients with classical Hodgkin's lymphoma: a study from the Groupe d'Etude des Lymphomes de l'Adulte.
Plasma cytokine signature is sufficient to predict disease-related outcome in classical Hodgkin's lymphoma, and allows the identification of patients with very high risk of treatment failure, adding significant prognostic information to its predictive power.
Antiphospholipid antibodies in adults with immune thrombocytopenic purpura
- C. Pierrot-Deseilligny Despujol, M. Michel, B. Godeau
- Medicine, BiologyBritish Journal of Haematology
- 1 August 2008
The significant associations between thrombosis and LA or high IgG‐aCL level or high aCL level suggest that aPL should be tested at ITP diagnosis.
High-Dose Immunoglobulin Therapy for Severe IgA Nephropathy and Henoch-Schonlein Purpura
High-dose intravenous immunoglobulins are effective in some human immune-mediated diseases and are postulated to favor viral and bacterial infections, a known trigger of flare-ups in these diseases, or activate noxious isotypic compensatory mechanisms in patients with severe IgAN and HSP who had indicators of poor prognosis.
Overproduction of proinflammatory cytokines imbalanced by their antagonists in POEMS syndrome.
The results suggest that the manifestations of POEMS syndrome might be regarded as the result of a marked activation of the proinflammatory cytokine network associated with a weak or even decreased (TGF beta 1) antagonistic reaction insufficient to counteract the noxious effects of cytokines.
Long lasting IgG subclass and antibacterial polysaccharide antibody deficiency after allogeneic bone marrow transplantation.
Most patients with Hib pneumonia showed virtually no IgG antibody response to Hib, and one-half of the patients had a moderate IgM and IgA response; however, the abnormalities are not clearly predictive of infections in individual cases.
Inflammatory response to cardiopulmonary bypass using roller or centrifugal pumps.
Specific antiplatelet glycoprotein autoantibodies are associated with the thrombocytopenia of primary antiphospholipid syndrome
- B. Godeau, J. Piette, P. Fromont, L. Intrator, A. Schaeffer, P. Bierling
- Biology, MedicineBritish Journal of Haematology
- 1 September 1997
The results suggest a link between specific platelet antibodies and the thrombocytopenia of PAPL and specifically bind in vivo to platelet Gps via their F(ab′)2 fragments.