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Incidence and outcomes of acute lung injury.
BACKGROUND Acute lung injury is a critical illness syndrome consisting of acute hypoxemic respiratory failure with bilateral pulmonary infiltrates that are not attributed to left atrial hypertension.Expand
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Clinical risks for development of the acute respiratory distress syndrome.
To further understanding of the epidemiology of acute respiratory distress syndrome (ARDS), we prospectively identified 695 patients admitted to our intensive care units from 1983 through 1985Expand
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Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome.
BACKGROUND Persistent acute respiratory distress syndrome (ARDS) is characterized by excessive fibroproliferation, ongoing inflammation, prolonged mechanical ventilation, and a substantial risk ofExpand
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Surfactant chemical composition and biophysical activity in acute respiratory distress syndrome.
Acute Respiratory Distress Syndrome (ARDS) is characterized by lung injury and damage to the alveolar type II cells. This study sought to determine if endogenous surfactant is altered in ARDS.Expand
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Cytokine balance in the lungs of patients with acute respiratory distress syndrome.
Acute respiratory distress syndrome (ARDS) involves an intense inflammatory response in the lungs, with accumulation of both pro- and antiinflammatory cytokines in bronchoalveolar lavage fluidExpand
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Inflammatory cytokines in patients with persistence of the acute respiratory distress syndrome.
To determine the relationship between airspace cytokines and cellular inflammatory responses in patients with the acute respiratory distress syndrome (ARDS), we performed bronchoalveolar lavage (BAL)Expand
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Causes of Mortality in Patients with the Adult Respiratory Distress Syndrome
This study analyzed the factors causing and contributing to death in patients with the adult respiratory distress syndrome (ARDS). Two hundred seven patients were prospectively identified as being atExpand
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Bovine surfactant therapy for patients with acute respiratory distress syndrome.
Lung surfactant is deficient in patients with acute respiratory distress syndrome (ARDS). We performed a randomized, prospective, controlled, open-label clinical study of administration of a bovineExpand
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Serial changes in surfactant-associated proteins in lung and serum before and after onset of ARDS.
The goal of this study was to determine the changes that occur in surfactant-associated proteins in bronchoalveolar lavage fluid (BAL) and serum of patients at risk for ARDS and during the course ofExpand
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Neutrophil apoptosis in the acute respiratory distress syndrome.
Little is known about neutrophil (PMN) apoptosis in the acute respiratory distress syndrome (ARDS). We uses morphologic criteria to count apoptotic PMN in bronchoalveolar lavage fluid (BAL) of 35Expand
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