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Arsenic methylation capacity, body retention, and null genotypes of glutathione S-transferase M1 and T1 among current arsenic-exposed residents in Taiwan.
Ingested arsenic, characteristics of well water consumption and risk of different histological types of lung cancer in northeastern Taiwan.
Ingested arsenic, cigarette smoking, and lung cancer risk: a follow-up study in arseniasis-endemic areas in Taiwan.
There was a significant dose-response trend of ingested arsenic on lung cancer risk, which was more prominent among cigarette smokers, and the risk assessment of lung cancer induced by ingested arsenic should take cigarette smoking into consideration.
Arsenic in Drinking Water and Risk of Urinary Tract Cancer: A Follow-up Study from Northeastern Taiwan
- Chi-Ling Chen, H. Chiou, Chien-Jen Chen
- MedicineCancer Epidemiology, Biomarkers and Prevention
- 1 January 2010
Analysis of the relationship between ingested arsenic and urinary cancer in lower exposure groups and the influence of duration, recency, and latency of drinking arsenic-containing well water found that those exposed to relatively lower concentrations had a significantly increased risk of urinary cancer.
Biological Gradient Between Long-Term Arsenic Exposure and Carotid Atherosclerosis
Carotid atherosclerosis is associated with ingested inorganic arsenic, showing a significant biological gradient, and remained significant after adjustment for age, sex, hypertension, diabetes mellitus, cigarette smoking, alcohol consumption, waist-to-hip ratio, and serum levels of total cholesterol and LDL cholesterol.
A review of the epidemiologic literature on the role of environmental arsenic exposure and cardiovascular diseases.
Arsenic exposure, urinary arsenic speciation, and the incidence of urothelial carcinoma: a twelve-year follow-up study
There was a significant association between inefficient arsenic methylation and the development of UC in the residents in the high CAE exposure strata in an area of southwestern Taiwan endemic for arseniasis.
Biomarkers of exposure, effect, and susceptibility of arsenic-induced health hazards in Taiwan.
Genetic variants in ARID5B and CEBPE are childhood ALL susceptibility loci in Hispanics
Although IKZF1 loci showed significant susceptibility effects among NHWs, their effects among Hispanics were in the same direction but nonsignificant, despite similar minor allele frequencies, and future studies should examine whether the observed effects vary by environmental, immunological, or lifestyle factors.
Novel childhood ALL susceptibility locus BMI1-PIP4K2A is specifically associated with the hyperdiploid subtype.
A recent genome-wide association study of childhood acute lymphoblastic leukemia (ALL) has identified a novel susceptibility locus encompassing BMI1 - PIP4K2A at chr10p12.31-12.2, bringing the number of known ALL risk loci to 5.