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Prebiotic effects: metabolic and health benefits
The different compartments of the gastrointestinal tract are inhabited by populations of micro-organisms. By far the most important predominant populations are in the colon where a true symbiosisExpand
Akkermansia muciniphila and improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology
Objective Individuals with obesity and type 2 diabetes differ from lean and healthy individuals in their abundance of certain gut microbial species and microbial gene richness. Abundance ofExpand
Molecular Phenomics and Metagenomics of Hepatic Steatosis in Non-Diabetic Obese Women
Hepatic steatosis is a multifactorial condition that is often observed in obese patients and is a prelude to non-alcoholic fatty liver disease. Here, we combine shotgun sequencing of fecalExpand
Colonic bacterial metabolites and human health.
The influence of the microbial-mammalian metabolic axis is becoming increasingly important for human health. Bacterial fermentation of carbohydrates (CHOs) and proteins produces short-chain fattyExpand
Quantifying Diet-Induced Metabolic Changes of the Human Gut Microbiome.
The human gut microbiome is known to be associated with various human disorders, but a major challenge is to go beyond association studies and elucidate causalities. Mathematical modeling of theExpand
Examination of faecal Bifidobacterium populations in breast- and formula-fed infants during the first 18 months of life.
Bifidobacteria in the infant faecal microbiota have been the focus of much interest, especially during the exclusive milk-feeding period and in relation to the fortification of infant formulae toExpand
Microbiome–host systems interactions: protective effects of propionate upon the blood–brain barrier
BackgroundGut microbiota composition and function are symbiotically linked with host health and altered in metabolic, inflammatory and neurodegenerative disorders. Three recognised mechanisms existExpand
Survivability of a probiotic Lactobacillus casei in the gastrointestinal tract of healthy human volunteers 
and its impact on the faecal microflora
Aim:  The aim of this study was to measure the gastrointestinal survival of Lactobacillus casei and its impact on the gut microflora in healthy human volunteers.
Metabolic retroconversion of trimethylamine N-oxide and the gut microbiota
BackgroundThe dietary methylamines choline, carnitine, and phosphatidylcholine are used by the gut microbiota to produce a range of metabolites, including trimethylamine (TMA). However, little isExpand
Characterization of virus-like particles associated with the human faecal and caecal microbiota.
This work represents an investigation into the presence, abundance and diversity of virus-like particles (VLPs) associated with human faecal and caecal samples. Various methodologies for the recoveryExpand