• Publications
  • Influence
Guidelines for the nomenclature of the human heat shock proteins
The expanding number of members in the various human heat shock protein (HSP) families and the inconsistencies in their nomenclature have often led to confusion. Here, we propose new guidelines forExpand
Heat shock, stress proteins, chaperones, and proteotoxicity
Abstract Cold Spring Harbor was the scene of the first international heat shock meeting, held in 1982 on the 20th anniversary year of Ferruccio Ritossa's discovery of the heat shock response.Expand
Selective release from cultured mammalian cells of heat‐shock (stress) proteins that resemble glia‐axon transfer proteins
Cultured rat embryo cells were stimulated to rapidly release a small group of proteins that included several heat‐shock proteins (hsp110, hsp71, hscp73) and nonmuscle actin. The extracellularExpand
Low-molecular-weight heat shock proteins in a desert fish (Poeciliopsis lucida): homologs of human Hsp27 and Xenopus Hsp30.
The heat shock response of a fish which inhabits a highly stressful environment (Poeciliopsis lucida, a minnow from river systems of the Sonoran desert in northwestern Mexico) was investigated. CellsExpand
Heat shock and thermotolerance during early rat embryo development.
Effects of heat shock on the development of early pre-somite embryos have been studied using cultured rat embryos. The results illustrate the sensitivity of the developing head and brain to elevatedExpand
Recent applications of fish cell culture to biomedical research.
Tissues of the fishes are as amenable to the techniques of modern cell culture as mammalian tissues and organs, and yet this vast resource, comprising thousands of vertebrate species, remains largelyExpand
Cell number‐dependent regulation of Hsp70B′ expression: Evidence of an extracellular regulator
Hsp70B′ is a unique member of the human Hsp70 family of chaperones about which information is scarce. Unlike the major inducible Hsp72 protein, Hsp70B′ is strictly inducible having little or no basalExpand
Evaluation of heavy‐metal ion toxicity in fish cells using a combined stress protein and cytotoxicity assay
All organisms, from bacteria and yeast to humans, respond to physical and chemical stressors by increasing the synthesis of a small group of cellular stress proteins.'' The authors have developed aExpand
Hyperbaric oxygen treatment induces antioxidant gene expression
Although the underlying molecular causes of aging are not entirely clear, hormetic agents like exercise, heat, and calorie restriction may generate a mild pro‐oxidant stress that induces cellExpand
Cultured animal cells exposed to amino acid analogues or puromycin rapidly synthesize several polypeptides
  • L. Hightower
  • Biology, Medicine
  • Journal of cellular physiology
  • 1 March 1980
Four major acidic polypeptides, with molecular weights of 88, 72, 71, and 23 thousand, and minor polypeptides with molecular weights of 110, 50, 38, and 30 thousand rapidly accumulated in culturedExpand
...
1
2
3
4
5
...