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The prevention of infection in open fractures: an experimental study of the effect of fracture stability.
An experimental model of a contaminated open fracture has been developed. This model has been used to test the hypothesis that stable fixation of a contaminated open fracture will reduce itsExpand
An experimental model of post-traumatic osteomyelitis in rabbits.
An experimental model of a contaminated open fracture, using the tibia of male New Zealand white rabbits, is described. Post-traumatic osteomyelitis can be reliably induced in this model, with noExpand
Ciprofloxacin therapy of infections caused by Pseudomonas aeruginosa and other resistant bacteria.
Ciprofloxacin was administered orally to 48 patients with 24 Pseudomonas aeruginosa infections and 13 other infections caused by cephalothin-resistant gram-negative bacilli. The types of infectionsExpand
Antibiotic therapy of osteomyelitis in outpatients.
The therapy of osteomyelitis utilizing 481 courses of intravenous antibiotics in outpatients was analyzed to identify the types of bone infection most frequently treated by this form of therapy. TheExpand
Osteomalacia and femoral neck fractures in the elderly patient.
In a series of over 1000 elderly patients with femoral neck fracture, who were routinely screened by iliac crest bone biopsy, a 2% prevalence of osteomalacia was found. This low figure suggests thatExpand
The prevention of infection in open fractures. An experimental study of the effect of antibiotic therapy.
Using an experimental rabbit model of a contaminated open fracture of the tibia that was fixed with an intramedullary pin, we assessed the effect of a single dose of cephradine in preventingExpand
Interferon in the prevention of genital herpes recurrence.
Patients with genital herpes were treated three times weekly for 12 weeks with 3 X 10(6) IU of alpha 2b interferon (20 patients) or placebo (17 patients) administered by subcutaneous injection in aExpand
Screening for osteomalacia in elderly patients with femoral neck fractures.
In this study 201 elderly patients with femoral neck fractures were compared with 30 osteomalacic patients with the same injury. Hypocalcaemia and a raised alkaline phosphatase level are commonExpand
The Prevention of Infection in Open Fractures
Using an experimental rabbit model of a contaminated open fracture of the tibia that was fixed with an intramedullary pin, we assessed the effect of a single dose of cephradine in preventingExpand
A Trial Using Early Preoperative Administration of Cefonicid for Antimicrobial Prophylaxis with Hysterectomies
A single dose of cefonicid given 3.5–5.0 hours or 0.5–1.0 hour preoperatively was compared with cefoxitin given as five doses beginning 0.5–1.0 hour preoperatively for prophylaxis of infection in 202Expand
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