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MUC1, MUC2, MUC5AC, and MUC6 in colorectal cancer: expression profiles and clinical significance
Mucin glycoprotein expression can be altered during the carcinogenic process. The impact on the prognosis of patients with colorectal cancer (CRC) is controversial. We analyzed tumors from 381… Expand
Tumor necrosis is a new promising prognostic factor in colorectal cancer.
The prognostic significance of tumor necrosis in colorectal cancer is unclear. Our study aimed to analyze the prognostic value of tumor necrosis with respect to progression-free and cancer-specific… Expand
Mucinous differentiation in colorectal cancer – indicator of poor prognosis?
Langner C, Harbaum L, Pollheimer M J, Kornprat P, Lindtner R A, Schlemmer A, Vieth M & Rehak P (2012) Histopathology 60, 1060–1072
Keratin 7 expression in colorectal cancer – freak of nature or significant finding?
Harbaum L, Pollheimer M J, Kornprat P, Lindtner R A, Schlemmer A, Rehak P & Langner C (2011) Histopathology59, 225–234
Clinicopathological significance of prolactin receptor expression in colorectal carcinoma and corresponding metastases
The role of human prolactin and its receptor, the prolactin receptor, in colorectal cancer is largely unknown. Our study aimed to assess the prevalence of prolactin receptor expression, its… Expand
Recent advances in pulmonary arterial hypertension
Pulmonary arterial hypertension (PAH) is a rare disorder with a high mortality rate. Treatment options have improved in the last 20 years, but patients still die prematurely of right heart failure.… Expand
Sporadic gastric Peutz‐Jeghers polyp with intraepithelial neoplasia
- L. Harbaum, J. Geigl, +4 authors C. Langner
- APMIS : acta pathologica, microbiologica, et…
- 1 December 2009
Peutz-Jeghers syndrome (PJS) is a rare, autosomal dominantly inherited disease, linked to a germline mutation in the STK11 gene (previously named LKB1) coding for a serine ⁄ threonine kinase on… Expand
Lymph node retrieval in colorectal cancer: determining factors and prognostic significance
- J. Betge, L. Harbaum, +4 authors C. Langner
- International Journal of Colorectal Disease
- 16 February 2017
PurposeThe study aimed to analyze clinicopathological factors that determine the extent of lymph node retrieval and to evaluate its prognostic impact in patients with colorectal cancer… Expand
Tumour budding with and without admixed inflammation: two different sides of the same coin?
- Nicole Max, L. Harbaum, M. Pollheimer, R. Lindtner, P. Kornprat, C. Langner
- Biology, Medicine
- British Journal of Cancer
- 14 January 2016
Background:Tumour budding is an adverse prognostic indicator in colorectal cancer (CRC). Marked overall peritumoural inflammation has been associated with favourable outcome and may lead to the… Expand
Acute effects of exercise on the inflammatory state in patients with idiopathic pulmonary arterial hypertension
BackgroundExercise training positively influences exercise tolerance and functional capacity of patients with idiopathic pulmonary arterial hypertension (IPAH). However, the underlying mechanisms are… Expand