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Biochemical and structural characterisation of membrane-containing icosahedral dsDNA bacteriophages infecting thermophilic Thermus thermophilus.
Icosahedral dsDNA viruses isolated from hot springs and proposed to belong to the Tectiviridae family infect the gram-negative thermophilic Thermus thermophilus bacterium. Seven such viruses wereExpand
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Familial Relationships in Hyperthermo- and Acidophilic Archaeal Viruses
ABSTRACT Archaea often live in extreme, harsh environments such as acidic hot springs and hypersaline waters. To date, only two icosahedrally symmetric, membrane-containing archaeal viruses, SH1 andExpand
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Characterization of the Genome, Proteome, and Structure of Yersiniophage ϕR1-37
ABSTRACT The bacteriophage vB_YecM-ϕR1-37 (ϕR1-37) is a lytic yersiniophage that can propagate naturally in different Yersinia species carrying the correct lipopolysaccharide receptor. ThisExpand
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Generation of Single-Copy Transposon Insertions in Clostridium perfringens by Electroporation of Phage Mu DNA Transposition Complexes
ABSTRACT Transposon mutagenesis is a tool that is widely used for the identification of genes involved in the virulence of bacteria. Until now, transposon mutagenesis in Clostridium perfringens hasExpand
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Bacteriophage Mu integration in yeast and mammalian genomes
Genomic parasites have evolved distinctive lifestyles to optimize replication in the context of the genomes they inhabit. Here, we introduced new DNA into eukaryotic cells using bacteriophage Mu DNAExpand
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Interaction with the host: the role of fibronectin and extracellular matrix proteins in the adhesion of Gram-negative bacteria
The capacity of pathogenic microorganisms to adhere to host cells and avoid clearance by the host immune system is the initial and most decisive step leading to infections. Bacteria have developedExpand
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Yersinia enterocolitica-Specific Infection by Bacteriophages TG1 and ϕR1-RT Is Dependent on Temperature-Regulated Expression of the Phage Host Receptor OmpF
ABSTRACT Bacteriophages present huge potential both as a resource for developing novel tools for bacterial diagnostics and for use in phage therapy. This potential is also valid for bacteriophagesExpand
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Comprehensive Mass Spectrometric Survey of Streptococcus pyogenes Subcellular Proteomes.
Streptococcus pyogenes is a major global health burden causing a wide variety of diseases. Because a vaccine against this bacterium is still lacking, vaccine candidates or antimicrobial therapies areExpand
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Functional and Structural Properties of a Novel Protein and Virulence Factor (Protein sHIP) in Streptococcus pyogenes *
Background: We searched for novel extracellular proteins in Streptococcus pyogenes. Results: A protein (sHIP) protecting S. pyogenes against antibacterial activity was identified. Its structure wasExpand
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