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HPA axis activation by a socially evaluated cold-pressor test
TLDR
Findings indicate that the incorporation of social-evaluative elements increases HPA axis responses to the CPT, and the SECPT can serve as a tool for future stress research. Expand
Test–retest reliability of resting-state connectivity network characteristics using fMRI and graph theoretical measures
TLDR
This study provides methodological recommendations which allow the computation of sufficiently robust markers of network organization using graph metrics derived from fMRI data at rest using several commonly used measures from the field of graph theory. Expand
Dynamic reconfiguration of frontal brain networks during executive cognition in humans
TLDR
The results characterize dynamic reconfiguration of large-scale distributed neural circuits during executive cognition in humans and have implications for understanding impaired cognitive function in disorders affecting connectivity, such as schizophrenia or dementia. Expand
City living and urban upbringing affect neural social stress processing in humans
TLDR
It is shown that urban upbringing and city living have dissociable impacts on social evaluative stress processing in humans, and distinct neural mechanisms for an established environmental risk factor are identified. Expand
Test–retest reliability of evoked BOLD signals from a cognitive–emotive fMRI test battery
TLDR
All three tasks in the combined three-task fMRI battery targeting three systems of wide applicability in clinical and cognitive neuroscience are well suited to between-subject designs, including imaging genetics. Expand
Neural Mechanisms of a Genome-Wide Supported Psychosis Variant
TLDR
These findings establish disturbed connectivity as a neurogenetic risk mechanism for psychosis supported by genome-wide association, show that rs1344706 or variation in linkage disequilibrium is functional in human brain, and validate the intermediate phenotype strategy in psychiatry. Expand
Test–retest reliability of fMRI-based graph theoretical properties during working memory, emotion processing, and resting state
TLDR
The test-retest reliability of brain graphs calculated from 26 healthy participants with three established fMRI experiments and two parcellation schemes for node definition are studied to inform the choice of processing strategies, brain atlases and outcome properties for fMRI studies using active tasks, graph theory methods and within-subject designs. Expand
Amygdala habituation: A reliable fMRI phenotype
TLDR
The results show that emotion-dependent amygdala habituation is a robust and considerably more reliable index than the mean amplitude, and provides a robust potential endpoint for within-subject designs including pharmaco-fMRI studies. Expand
Cognitive state and connectivity effects of the genome-wide significant psychosis variant in ZNF804A
TLDR
A key role for disturbed functional connectivity in the genetic risk architecture of schizophrenia is confirmed and cognitive state-dependent and independent components with regard to WM function are identified. Expand
Brain function in carriers of a genome-wide supported bipolar disorder variant.
TLDR
Healthy carriers of the CACNA1C risk variant exhibit a pronounced reduction of bilateral hippocampal activation during episodic memory recall and diminished functional coupling between left and right hippocampal regions, demonstrating that rs1006737 or genetic variants in linkage disequilibrium with it are functional in the human brain. Expand
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