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Therapy of tuberculosis in mice by DNA vaccination
Mycobacterium tuberculosis continues to kill about 3 million people every year, more than any other single infectious agent. This is attributed primarily to an inadequate immune response towards… Expand
Role of Trehalose Dimycolate in Recruitment of Cells and Modulation of Production of Cytokines and NO in Tuberculosis
ABSTRACT Mice treated with viable Mycobacterium tuberculosis with no glycolipid trehalose dimycolate (TDM) on the outer cell wall (delipidated M. tuberculosis) by intraperitoneal or intratracheal… Expand
Circulating interleukin-6 and high-sensitivity C-reactive protein decrease after periodontal therapy in otherwise healthy subjects.
- A. Marcaccini, C. A. Meschiari, +6 authors R. F. Gerlach
- Journal of periodontology
- 1 April 2009
BACKGROUND Periodontal disease has been associated with many chronic inflammatory systemic diseases, and a common chronic inflammation pathway has been suggested for these conditions. However, few… Expand
Anti-inflammatory activity of quercetin and isoquercitrin in experimental murine allergic asthma
Abstract.Objective:Eosinophils and cytokines are implicated in the pathogenesis of allergic diseases. In the present study, we investigate the anti-inflammatory effect of quercetin and isoquercitrin… Expand
Circulating matrix metalloproteinase-8 (MMP-8) and MMP-9 are increased in chronic periodontal disease and decrease after non-surgical periodontal therapy.
- A. Marcaccini, A. Novaes, +6 authors R. F. Gerlach
- Clinica chimica acta; international journal of…
- 3 November 2009
BACKGROUND Periodontal disease shares risk factors with cardiovascular diseases and other systemic inflammatory diseases. The present study was designed to assess the circulating matrix… Expand
Inflammatory response to different endodontic irrigating solutions.
- M. Tanomaru Filho, M. Leonardo, L. Silva, F. F. Anibal, L. H. Faccioli
- International endodontic journal
- 1 September 2002
AIM The aim of this study was to evaluate the inflammatory response to irrigating solutions injected into the peritoneal cavity of mice. METHODOLOGY Sixty mice received intra-peritoneal injections… Expand
The uptake of PLGA micro or nanoparticles by macrophages provokes distinct in vitro inflammatory response.
- R. Nicolete, D. F. dos Santos, L. H. Faccioli
- Chemistry, Medicine
- International immunopharmacology
- 1 October 2011
Biodegradable micro/nanoparticles generated from PLGA have recently attracted attention due to their clinically proven biocompatibility, especially for immunization purposes. These polymeric… Expand
Chlorogenic acids from Tithonia diversifolia demonstrate better anti-inflammatory effect than indomethacin and its sesquiterpene lactones.
- D. A. Chagas-Paula, R. B. Oliveira, +5 authors F. D. Da Costa
- Chemistry, Medicine
- Journal of ethnopharmacology
- 22 June 2011
ETHNOPHARMACOLOGICAL RELEVANCE T. diversifolia (Hemsl.) A. Gray (Asteraceae) has been used in the traditional medicine in several countries as anti-inflammatory and against other illnesses. It is… Expand
TLR2, TLR4 and CD14 Recognize Venom-Associated Molecular Patterns from Tityus serrulatus to Induce Macrophage-Derived Inflammatory Mediators
Scorpion sting-induced human envenomation provokes an intense inflammatory reaction. However, the mechanisms behind the recognition of scorpion venom and the induction of mediator release in… Expand
Opposing roles of LTB4 and PGE2 in regulating the inflammasome-dependent scorpion venom-induced mortality
- Karina F Zoccal, C. Sorgi, +5 authors L. H. Faccioli
- Biology, Medicine
- Nature communications
- 23 February 2016
Tityus serrulatus sting causes thousands of deaths annually worldwide. T. serrulatus-envenomed victims exhibit local or systemic reaction that culminates in pulmonary oedema, potentially leading to… Expand