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Narp and NP1 Form Heterocomplexes that Function in Developmental and Activity-Dependent Synaptic Plasticity
Narp is a neuronal immediate early gene that plays a role in excitatory synaptogenesis. Here, we report that native Narp in brain is part of a pentraxin complex that includes NP1. These proteins are… Expand
Isolation and identification of cancer stem-like cells in esophageal carcinoma cell lines.
Side population (SP) cells may play an important role in tumorigenesis and cancer therapy. We isolate and identify the cancer stem-like cells in human esophageal carcinoma (EC) cell lines, EC9706 and… Expand
GP73, a novel Golgi-localized protein upregulated by viral infection
Abstract We report the isolation and characterization of GP73, a novel 73kDa human Golgi protein. The GP73 cDNA was cloned by differential screening of a cDNA library derived from the liver of a… Expand
Overexpression of Aurora-A Contributes to Malignant Development of Human Esophageal Squamous Cell Carcinoma
Purpose: Aurora-A/STK15/BTAK, a centrosome-associated oncogenic protein, is implicated in the control of mitosis. Overexpression of Aurora-A has been shown to result in chromosomal aberration and… Expand
The oncogenetic role of microRNA-31 as a potential biomarker in oesophageal squamous cell carcinoma.
miR-31 (microRNA-31) is frequently altered in numerous cancers. The aim of the present study was to investigate the role of miR-31 in ESCC (oesophageal squamous cell carcinoma). We measured miR-31 in… Expand
Kif18A is involved in human breast carcinogenesis.
Microtubule (MT) kinesin motor proteins orchestrate various cellular processes (e.g. mitosis, motility and organelle transportation) and have been implicated in human carcinogenesis. Kif18A, a… Expand
The PTEN/PI3K/Akt pathway regulates stem-like cells in primary esophageal carcinoma cells
Recent reports have shown that cancer stem cells exist in many malignancies. Side population (SP) cells are used to enrich cancer stem-like cells in many cell lines and fresh tumor specimens. In this… Expand
The role of pre‐replicative complex (pre‐RC) components in oncogenesis
- E. Lau, T. Tsuji, L. Guo, S. Lu, W. Jiang
- Biology, Medicine
- FASEB journal : official publication of the…
- 1 December 2007
Normal DNA replication is stringently regulated to ensure a timely occurrence no more than once per cell cycle. Abrogation of the exquisite control mechanisms that maintain this process results in… Expand
The voltage-gated potassium channel Kv1.3 is highly expressed on inflammatory infiltrates in multiple sclerosis brain.
- H. Rus, C. Pardo, +14 authors P. Calabresi
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 2 August 2005
Multiple Sclerosis (MS) is characterized by central nervous system perivenular and parenchymal mononuclear cell infiltrates consisting of activated T cells and macrophages. We recently demonstrated… Expand
Prostatic arterial embolization for the treatment of lower urinary tract symptoms caused by benign prostatic hyperplasia: a comparative study of medium‐ and large‐volume prostates
To compare the outcomes of prostatic arterial embolization (PAE) in treating large (>80 mL) in comparison with medium‐sized prostate glands (50–80 mL) to determine whether size affects the outcome of… Expand