• Publications
  • Influence
Recombination in Escherichia coli and the definition of biological species.
The DNA sequence of part of the gnd (6-phosphogluconate dehydrogenase) gene was determined for eight wild strains of Escherichia coli and for Salmonella typhimurium. Since a region of the trpExpand
  • 381
  • 12
  • PDF
Detection of Escherichia coli ribosome binding at translation initiation sites in the absence of tRNA.
Binary complexes between messenger RNA and E. coli ribosomes were examined. A ribosome-mRNA binary complex on T4 gene 32 mRNA withstood inhibition by antibodies against ribosomal protein S1. Anti-S1Expand
  • 61
  • 4
Oligopeptidase-deficient mutants of Salmonella typhimurium.
An oligopeptidase that hydrolyzes N-acetyl-L-alanyl-L-alanyl-L-alanyl-L-alanine (AcAla4) has been identified in extracts of Salmonella typhimurium. Mutants lacking this activity have been isolated inExpand
  • 31
  • 2
Degradation of proline peptides in peptidase-deficient strains of Salmonella typhimurium.
A mutant strain of Salmonella typhimurium that lacks two proline-specific peptidases (peptidases P and Q) could not complete the degradation of proline peptides formed as intermediates inExpand
  • 25
  • 1
Degradation of intracellular protein in Salmonella typhimurium peptidase mutants.
Abstract Multiply peptidase-deficient mutant strains of Salmonella typhimurium fail to carry out normal protein degradation during starvation for a carbon source. In these mutants, the extent ofExpand
  • 76
  • 1
RNA ligands to human nerve growth factor.
High affinity RNA ligands to human nerve growth factor (NGF) were selected from pools of random RNA using SELEX [Tuerk, C. and Gold, L. (1990) Science, 249, 505-510]. Nerve growth factor, which is aExpand
  • 39
  • 1
Binding of the bacteriophage T4 regA protein to mRNA targets: an initiator AUG is required.
Bacteriophage T4 regA protein translationally represses the synthesis of a subset of early phage-induced proteins. The protein binds to the translation initiation site of at least two mRNAs andExpand
  • 26
  • 1
Degradation of abnormal proteins in peptidase-deficient mutants of Salmonella typhimurium.
The degradation of abnormal proteins produced as a result of incorporation of the arginine analog L-canavanine or generated by exposure to puromycin was studied in wild-type and multiplyExpand
  • 22
  • 1
Reevaluation of things past. A test of the "retrospection hypothesis" using a CER procedure with rats.
The ability of rats to reevaluate previously presented information in light of subsequently provided information was evaluated using a CER (conditioned emotional response) procedure. In Experiment 1,Expand
  • 15
  • 1