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RNF20 and USP44 regulate stem cell differentiation by modulating H2B monoubiquitylation.
Mutual protection of ribosomal proteins L5 and L11 from degradation is essential for p53 activation upon ribosomal biogenesis stress
- S. Bursać, Maja Cokarić Brdovčak, S. Volarevic
- BiologyProceedings of the National Academy of Sciences
- 20 November 2012
It is reported that the disrupted nucleoli may provide a platform for L5- and L11-dependent p53 activation, implying a role for the nucleolus in p53activation by ribosomal biogenesis stress.
Different subcellular localizations and functions of Arabidopsis myosin VIII
The data suggest that myosin VIII functions differently in different root cells and can be involved in different steps of endocytosis, BFA-sensitive and insensitive pathways, ER tethering and plasmodesmatal activity.
p53 and ribosome biogenesis stress: The essentials
Importin 7 and exportin 1 link c-Myc and p53 to regulation of ribosomal biogenesis.
Identification of plant cytoskeleton-interacting proteins by screening for actin stress fiber association in mammalian fibroblasts.
A functional genomic screen for the isolation of new plant cytoskeleton-binding proteins that uses a mammalian cell expression system is developed and ERD10, a member of the dehydrin family of proteins, was localized to actin stress fibers in rat fibroblasts.
Digital Humanities in the Library: Challenges and Opportunities for Subject Specialists
In the past decade there has been an intense growth in the number of library publishing services supporting faculty and students. Unified by a commitment to both access and service, library…
Multi-Omics Analysis Identifies MGA as a Negative Regulator of the MYC Pathway in Lung Adenocarcinoma
A novel MYC/MAX/MGA pathway is defined, in which MYC and MGA play opposite roles in protein interaction, transcriptional regulation, and cellular proliferation, and places MYC within a linear pathway analogous to cell-cycle or receptor tyrosine kinase/RAS/RAF pathways in lung adenocarcinomas.
Collecting Poetry for the Academic Library: An Evaluation of Poetry Prizes as Selection Tools
- L. Golomb
- 1 May 2011
Age-associated inflammation connects RAS-induced senescence to stem cell dysfunction and epidermal malignancy
It is shown that mutant H-Ras activation in mouse epidermis, a frequent event in cutaneous squamous cell carcinoma (SCC), elicits a differential outcome in aged versus young mice, which supports an age-dependent link between accumulation of senescent cells, immune infiltration and cancer progression.