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Nerve growth factor control of neuronal expression of angiogenetic and vasoactive factors
TLDR
The present investigation suggests that the increase of scg size induced by NGF and 6-OHDA + NGF is associated with neoangiogenesis, and that the induction of vasoactive and angiogenic factors in neurons represents a further and previously undisclosed effect of NGF. Expand
Proliferation and phenotype regulation in the subventricular zone during experimental allergic encephalomyelitis: in vivo evidence of a role for nerve growth factor.
TLDR
An increase in the proliferation activity in the SVZ during experimental allergic encephalomyelitis, a demyelinating disease widely used as an experimental model for human multiple sclerosis, indicates that cell populations inThe SVZ are regulated during inflammatory conditions and degenerative diseases involving oligodendrocytes and neurotrophins, including nerve growth factor, could participate in these phenomena. Expand
Thyroid hormone activates oligodendrocyte precursors and increases a myelin-forming protein and NGF content in the spinal cord during experimental allergic encephalomyelitis
TLDR
The possibility of promoting myelination in experimental allergic encephalomyelitis by recruiting progenitors and channeling them into oligodendroglial lineage through administration of thyroid hormone (T4) is explored. Expand
NOS mRNA in the paraventricular nucleus of young and old rats after immobilization stress.
TLDR
The present results suggest that nitric oxide in the PVN may be involved in the stress response and the differences observed in NOS mRNA between young and old rats could be related to an age-dependent different responsiveness to stressful stimuli. Expand
Cognitive deficit associated with cholinergic and nerve growth factor down-regulation in experimental allergic encephalomyelitis in rats.
TLDR
It is demonstrated that a selective deficit in learning and memory performance, as investigated by the Morris water maze test, is a consistent feature in rat encephalomyelitis, which correlates with a decline in choline acetyltransferase activity and nerve growth factor mRNA level in cerebral cortex, hippocampus, and basal forebrain. Expand
Neural stem cells and cholinergic neurons: Regulation by immunolesion and treatment with mitogens, retinoic acid, and nerve growth factor
TLDR
The results suggest that pharmacological control of endogenous neural stem cells can provide an additional opportunity for brain repair, and offer useful information for improving integration of transplanted cells into the mature brain. Expand
p75NTR-Immunoreactivity in the subventricular zone of adult male rats: Expression by cycling cells
TLDR
It is reported that neurotrophin low affinity receptor p75NTR is present in the subventricular zone (SVZ) in adult male rats and seems to be associated with cell cycle regulation in SVZ in adult rat brain. Expand
Nitric oxide is involved in male sexual behavior of rats.
TLDR
It is concluded that nitric oxide synthase is involved in the expression of male sexual activity, in spite of some inconsistencies that are hard to interpret. Expand
cDNA characterization and chromosomal mapping of two human homologues of the Drosophila dishevelled polarity gene.
TLDR
The structural and evolutionary characteristics suggest that mutations at their loci may be involved in neural and heart developmental defects. Expand
The γ-secretase modulator CHF5074 restores memory and hippocampal synaptic plasticity in plaque-free Tg2576 mice.
TLDR
The beneficial effects of CHF5074 treatment in young transgenic mice occurred at a stage that precedes plaque formation and were associated with a reduction in intraneuronal AβPP/Aβ and hyperphosphorylated tau. Expand
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