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Natural history of alkaptonuria.
TLDR
Although nitisinone can reduce HGA production in humans with homogentisate 1,2-dioxygenase deficiency, the long-term safety and efficacy of this treatment require further evaluation. Expand
Biochemicals associated with pain and inflammation are elevated in sites near to and remote from active myofascial trigger points.
TLDR
The feasibility of continuous, in vivo recovery of small molecules from soft tissue without harmful effects is shown and the milieu of the gastrocnemius in subjects with active MTPs in the trapezius differs from subjects without active MTFs. Expand
Long-term treatment of hypoparathyroidism: a randomized controlled study comparing parathyroid hormone-(1-34) versus calcitriol and calcium.
TLDR
Treatment with twice daily sc PTH provides a safe and effective alternative to calcitriol therapy and is able to maintain normal serum calcium levels without hypercalciuria for at least 3 yr in patients with hypoparathyroidism. Expand
An in vivo microanalytical technique for measuring the local biochemical milieu of human skeletal muscle.
TLDR
In conclusion, the described microanalytical technique enables continuous sampling of extremely small quantities of substances directly from soft tissue, with minimal system perturbation and without harmful effects on subjects. Expand
Preoperative assessment enables the early diagnosis and successful treatment of lymphedema
TLDR
The authors demonstrated the effectiveness of a surveillance program that included preoperative limb volume measurement and interval postoperative follow-up to detect and treat subclinical LE. Expand
Constraint-Induced Therapy in Stroke: Magnetic-Stimulation Motor Maps and Cerebral Activation
TLDR
Cerebral activation during a motor task decreased significantly, and motor map size increased in the affected hemisphere motor cortex in CI patients but not in control patients, which may reflect improved ability of upper motor neurons to produce movement. Expand
Exercise Guidelines for Cancer Survivors: Consensus Statement from International Multidisciplinary Roundtable
TLDR
Enough evidence was available to conclude that specific doses of aerobic, combined aerobic plus resistance training, and/or resistance training could improve common cancer-related health outcomes, including anxiety, depressive symptoms, fatigue, physical functioning, and health-related quality of life. Expand
Controlled Trial of Pamidronate in Children With Types III and IV Osteogenesis Imperfecta Confirms Vertebral Gains but Not Short‐Term Functional Improvement
TLDR
A randomized controlled trial of q3m intravenous pamidronate in children with types III and IV OI yielded positive vertebral changes in DXA and geometry after 1 year of treatment, but no further significant improvement during extended treatment. Expand
Novel applications of ultrasound technology to visualize and characterize myofascial trigger points and surrounding soft tissue.
TLDR
Preliminary findings show that, under the conditions of this investigation, US imaging techniques can be used to distinguish myofascial tissue containing MTrPs from normal myofAscial tissue (lacking trigger points). Expand
Surface movement errors in shank kinematics and knee kinetics during gait
Abstract The movement of surface mounted targets (SMT) on a shell at the mid-shank and of bone mounted targets attached to the distal shank using a Percutaneous Skeletal Tracker (PST) wereExpand
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