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Gain-of-function mutation of GATA-2 in acute myeloid transformation of chronic myeloid leukemia
- S. Zhang, L. Ma, +11 authors S. Chen
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 12 February 2008
Acquisition of additional genetic and/or epigenetic abnormalities other than the BCR/ABL fusion gene is believed to cause disease progression in chronic myeloid leukemia (CML) from chronic phase to… Expand
Major Evolutionary Trends in Hydrogen Isotope Fractionation of Vascular Plant Leaf Waxes
Hydrogen isotopic ratios of terrestrial plant leaf waxes (δD) have been widely used for paleoclimate reconstructions. However, underlying controls for the observed large variations in leaf wax δD… Expand
Evaluating the Validity of Current Mainstream Wearable Devices in Fitness Tracking Under Various Physical Activities: Comparative Study
- Junqing Xie, Dong Wen, L. Liang, Yuxi Jia, L. Gao, Jianbo Lei
- Computer Science, Medicine
- JMIR mHealth and uHealth
- 1 April 2018
We evaluate the accuracy of latest wearable devices in measuring fitness-related indicators under various seminatural activities. Expand
Oridonin, a diterpenoid extracted from medicinal herbs, targets AML1-ETO fusion protein and shows potent antitumor activity with low adverse effects on t(8;21) leukemia in vitro and in vivo.
Studies have documented the potential antitumor activities of oridonin, a compound extracted from medicinal herbs. However, whether oridonin can be used in the selected setting of hematology/oncology… Expand
Nasopharyngeal carcinoma treated by radical radiotherapy alone: Ten-year experience of a single institution.
PURPOSE To report on our experience in the treatment of nasopharyngeal carcinoma (NPC) by radical radiotherapy alone in our institution during the last decade. METHODS AND MATERIALS From January… Expand
Abnormal Pulmonary Function and Respiratory Muscle Strength Findings in Chinese Patients with Parkinson’s Disease and Multiple System Atrophy–Comparison with Normal Elderly
Background There have been limited comparative data regarding the investigations on pulmonary and respiratory muscle function in the patients with different parkinsonism disorders such as Parkinson’s… Expand
Optical negative refraction in ferrofluids with magnetocontrollability.
- Y. Gao, J. Huang, Y. Liu, L. Gao, K. Yu, X. Zhang
- Materials Science, Medicine
- Physical review letters
- 20 January 2010
We numerically demonstrate optical negative refraction in ferrofluids containing isotropic Fe3O4 nanoparticles, each having an isotropic Ag shell, in the presence of an external dc magnetic field H.… Expand
MicroRNA-424 Protects Against Focal Cerebral Ischemia and Reperfusion Injury in Mice by Suppressing Oxidative Stress
Background and Purpose— We previously showed that the microRNA miR-424 protects against permanent cerebral ischemic injury in mice by suppressing microglia activation. This study investigated the… Expand
MicroRNA-124 Suppresses the Transactivation of Nuclear Factor of Activated T Cells by Targeting Multiple Genes and Inhibits the Proliferation of Pulmonary Artery Smooth Muscle Cells*
Background: The NFAT signaling pathway is linked to pulmonary arterial hypertension. Results: MicroRNA screening revealed that miR-124 robustly inhibits NFAT activity, dephosphorylation, and nuclear… Expand
Ear deformations give bats a physical mechanism for fast adaptation of ultrasonic beam patterns.
- L. Gao, S. Balakrishnan, Weikai He, Zhen Yan, R. Müller
- Physics, Medicine
- Physical review letters
- 14 November 2011
A large number of mammals, including humans, have intricate outer ear shapes that diffract incoming sound in a direction- and frequency-specific manner. Through this physical process, the outer ear… Expand