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Isocoumarin derivatives and benzofurans from a sponge-derived Penicillium sp. fungus.
Ten new fungal metabolites, including three hydroisocoumarins, penicimarins A-C, and four benzofurans, peniifurans A-D, together with four known isocou marin derivatives (4, 5, 9, 10), were obtained from the sponge-derived fungus Penicillium sp. Expand
Sesquiterpene lactones from the root tubers of Lindera aggregata.
Five new sesquiterpene lactones, linderagalactones A-E (1-5), linderane, hydroxylindestenolide, and linderalactone showed hepatoprotective activity against H2O2-induced oxidative damages on HepG2 cells with EC(50) values of 67.5, 167.4, and 98.0 microM, respectively. Expand
Antifouling and Fungicidal Resorcylic Acid Lactones from the Sea Anemone-Derived Fungus Cochliobolus lunatus.
Three new 14-membered resorcylic acid lactones, cochliomycins D-F, 1-3, and eight known analogues, 4-11, were isolated from the sea anemone-derived fungus Cochliobolus lunatus, and preliminary structure-activity relationships are discussed. Expand
Ciliatonoids A and B, Two Limonoids from Toona ciliata.
Three new ring B-seco limonoids, ciliatonoids A-C (1-3), were isolated from Toona ciliate and structurally characterized by spectroscopic data, X-ray crystallography, and electronic circularExpand
Eucarobustols A-I, Conjugates of Sesquiterpenoids and Acylphloroglucinols from Eucalyptus robusta.
Nine new conjugates of sesquiterpenoids and acylphloroglucinols, named eucarobustols A-I (1-9), as well as 11 known analogues were isolated from the leaves of Eucalyptus robusta, with inhibitory activities against protein tyrosine phosphatase 1B. Expand
Alkaloids from Lindera Aggregata
Among them, the 1D NMR chemical shifts of (+)-norboldine (2) showed a remarkable environmental sensitive behavior, and all the alkaloids were tested in cytotoxicity assays against L1210 and K562 tumor cell lines; only (+)-Norboldine showed weak activity against the L 1210 cell line. Expand
Isolation, resolution and biological evaluation of pestalachlorides E and F containing both point and axial chirality
Marine life forms are an important source of structurally diverse and biologically active natural products. As a unique case of both enantiomeric and atropisomeric isomers being present in one marineExpand
Antibacterial Biphenanthrenes from the Fibrous Roots of Bletilla striata.
Four new 9',10'-dihydro-biphenanthrenes, including an unprecedented 1,2'-linked biphenanthrene, are isolated from a 95% ethanol extract of the fibrous roots of Bletilla striata and showed potent antibacterial activities against six Gram-positive bacterial strains. Expand
Constituents of Trigonostemon chinensis.
Phytochemical investigation on the stem bark and wood of Trigonostemon chinensis led to the isolation of four new dinorditerpenoids, trigonostemons A-D (1, 3, 5, 6), a new phenanthrenone,Expand
Cephalotanins A-D, Four Norditerpenoids Represent Three Highly Rigid Carbon Skeletons from Cephalotaxus sinensis.
Four polycyclic norditerpenoids, cephalotanins A-D (1-4) representing three unprecedented carbon skeletons with highly rigid ring systems, were isolated from Cephalotaxus sinensis and structurallyExpand