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Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin.
Experimental autoimmune encephalomyelitis (EAE) is an inflammatory condition of the central nervous system with similarities to multiple sclerosis. In both diseases, circulating leukocytes penetrateExpand
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Prevention of experimental autoimmune encephalomyelitis by antibodies against α4βl integrin
EXPERIMENTAL autoimmune encephalomyelitis (EAE) is an inflammatory condition of the central nervous system with similarities to multiple sclerosis1,2. In both diseases, circulating leukocytesExpand
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A RAPID SIMPLE TECHNIQUE UTILIZING CALCOFLUOR WHITE M2R FOR THE VISUALIZATION OF DINOFLAGELLATE THECAL PLATES 1
The fluorescent stain Calcofluor White M2R readily binds to cellulose and other β‐linked glucans (Hughs and McCully 1975). We have found the stain to readily bind to the thecal plates of armoredExpand
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In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains.
Emerging evidence suggests that an amplifiable protease cascade consisting of multiple aspartate specific cysteine proteases (ASCPs) is responsible for the apoptotic changes observed in mammalianExpand
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AN OUTBREAK OF DOMOIC ACID POISONING ATTRIBUTED TO THE PENNATE DIATOM PSEUDONITZSCHIA AUSTRALIS 1
A bloom of the pennate diatom Pseudonitzschia australis Frenguelli (= Nitzschia pseudoseriata Hasle) occurring in Monterey Bay, California, in early September 1991 coincided with an episode ofExpand
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Cell-specific Induction of Apoptosis by Microinjection of Cytochrome c
Bcl-xL, an antiapoptotic member of the Bcl-2 family, inhibits programmed cell death in a broad variety of cell types. Recent reports have demonstrated that cytochromec is released from mitochondriaExpand
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Activation of the CED3/ICE-Related Protease CPP32 in Cerebellar Granule Neurons Undergoing Apoptosis But Not Necrosis
Neuronal apoptosis occurs during nervous system development and after pathological insults to the adult nervous system. Inhibition of CED3/ICE-related proteases has been shown to inhibit neuronalExpand
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Secretion of beta-amyloid precursor protein cleaved at the amino terminus of the beta-amyloid peptide.
The accumulation in brain of senile plaques containing beta-amyloid protein (A beta) is a defining feature of Alzheimer's disease. The amyloid precursor protein (APP)4 from which A beta is derived isExpand
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Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues.
Progressive cerebral deposition of extracellular filaments composed of the beta-amyloid protein (beta AP) is a constant feature of Alzheimer disease (AD). Since the gene on chromosome 21 encoding theExpand
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Fas-induced Activation of the Cell Death-related Protease CPP32 Is Inhibited by Bcl-2 and by ICE Family Protease Inhibitors*
The human proto-oncogene bcl-2 and its Caenorhabditis elegans homologue ced-9 inhibit programmed cell death. In contrast, members of the human interleukin-1β converting enzyme (ICE) family ofExpand
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