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Nitric Oxide Inhibitors Ameliorate Indomethacin-Induced Enteropathy in Rats
TLDR
The data suggest that NO derived from iNOS may be a key factor in the pathogenesis of acute INDO-induced enteropathy in rats. Expand
Expression of inducible nitric oxide synthase (iNOS) in rat intestinal mucosa by indomethacin
TLDR
INDO treatment increases iNOS expression in small intestinal mucosa as early as 3 and 4 days with concomitant increased ulcer length and MPO activity, suggesting that NO produced by iNos may contribute to the development of ulceration and inflammation in INDOinduced enteropathy. Expand