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Aneurysmal Coronary Artery Disease
To examine the clinical and historical features and the natural history of aneurysmal coronary disease, we reviewed the registry data of the Coronary Artery Surgery Study (CASS). Nine hundred… Expand
Veno-occlusive Disease of the Liver and Multiorgan Failure after Bone Marrow Transplantation: A Cohort Study of 355 Patients
Survival after bone marrow transplantation depends on recovery from the effects of cytoreductive therapy, successful engraftment, prevention of infections and graft-versus-host disease, and… Expand
Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B.
BACKGROUND AND METHODS The effect of intensive lipid-lowering therapy on coronary atherosclerosis among men at high risk for cardiovascular events was assessed by quantitative arteriography. Of 146… Expand
Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease.
BACKGROUND Both lipid-modifying therapy and antioxidant vitamins are thought to have benefit in patients with coronary disease. We studied simvastatin-niacin and antioxidant-vitamin therapy, alone… Expand
A Prospective Study of Work Perceptions and Psychosocial Factors Affecting the Report of Back Injury
A longitudinal, prospective study was conducted on 3,020 aircraft employees to identify risk factors for reporting acute back pain at work. The premorbid data included individual physical,… Expand
Prognosis in primary biliary cirrhosis: Model for decision making
- E. Dickson, Patricia M. Grambsch, T. R. Fleming, L. Fisher, A. Langworthy
- 1 July 1989
The ideal mathematical model for predicting survival for individual patients with primary biliary cirrhosis should be based on a small number of inexpensive, noninvasive measurements that are… Expand
Self-designing clinical trials.
- L. Fisher
- Medicine, Mathematics
- Statistics in medicine
- 30 July 1998
I present a method of sequential analysis for randomized clinical trials that allows use of all prior data in a trial to determine the use and weighting of subsequent observations. One continues to… Expand
Comparative reliability and validity of chronic pain intensity measures
Reliable and valid measures of pain are essential for conducting research on chronic pain. The purpose of this longitudinal study was to compare the reliability and validity of several measures of… Expand
Primary sclerosing cholangitis: Natural history, prognostic factors and survival analysis
The natural history of primary sclerosing cholangitis was assessed in 174 patients; 37 were asymptomatic and 137 had symptoms related to underlying liver disease. At the time of diagnosis, the mean… Expand
Time-dependent covariates in the Cox proportional-hazards regression model.
The Cox proportional-hazards regression model has achieved widespread use in the analysis of time-to-event data with censoring and covariates. The covariates may change their values over time. This… Expand