L. Ferrigno

Publications68
h-index21
Citations2,876
Highly Influential Citations71
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Exposure to foodborne and orofecal microbes versus airborne viruses in relation to atopy and allergic asthma: epidemiological study
TLDR
Respiratory allergy is less frequent in people heavily exposed to orofecal and foodborne microbes andgiene and a westernised, semisterile diet may facilitate atopy by influencing the overall pattern of commensals and pathogens that stimulate the gut associated lymphoid tissue thus contributing to the epidemic of allergic asthma and rhinitis in developed countries.
Hay fever and asthma in relation to markers of infection in the United States.
TLDR
Serologic evidence of acquisition of certain infections, mainly food-borne and orofecal infection, is associated with a lower probability of having hay fever and asthma in the United States.
Cross sectional retrospective study of prevalence of atopy among Italian military students with antibodies against hepatitis a virus
TLDR
Indirect but important evidence is added to the working hypothesis as common infections acquired early in life because of the presence of many older siblings or because of unhygienic living conditions (among seropositive subjects) may have reduced the risk of developing atopy.
Association of persistent bronchial hyperresponsiveness with beta2-adrenoceptor (ADRB2) haplotypes. A population study.
TLDR
It is observed that the ADRB2 haplotype with a Gly at position 16 and a Gln at position 27 is associated withBronchial hyperresponsiveness in a large, highly homogeneous sample of individuals, suggesting that AD RB2 gene can confer genetic susceptibility to BHR, rather than having only a disease-modifying effect in asthma.
Multispecific T cell response and negative HCV RNA tests during acute HCV infection are early prognostic factors of spontaneous clearance
TLDR
The results suggest that host related factors, in particular sex and CMI, play a crucial role in the spontaneous clearance of this virus and could thus be used as criteria in selecting candidates for early antiviral treatment.
The importance of HCV on the burden of chronic liver disease in Italy: A multicenter prevalence study of 9,997 cases
TLDR
It is indicated that nearly one quarter of patients with chronic liver diseases in Italy have a severe disease such as liver cirrhosis and HCC represents a not negligible burden for the national health system.
Allergy, asthma and markers of infections among Albanian migrants to Southern Italy
Background:  Studies of immigrants represent an useful tool to determine the relative relevance of environmental vs genetic factors in causing the reported rapid increase of the prevalence of…
Characteristics of liver cirrhosis in Italy: results from a multicenter national study.
TLDR
The results of the present study show that in Italy, liver cirrhosis is mainly associated with hepatitis C virus infection, reflecting the high prevalence of this infection in the general population.
Associations Between Plasma Levels of Vitamins and Cataract in the Italian-American Clinical Trial of Nutritional Supplements and Age-Related Cataract (CTNS): CTNS Report #2
TLDR
Higher plasma levels of vitamin C were found to be associated with reduced prevalence of N and PSC cataracts, and the finding of an increased prevalence of some types of cataract with higher levels of Vitamin E was unexpected, has not been previously reported, and could be due to unadjusted confounding.
Sibship size, birth order, and atopy in 11,371 Italian young men.
TLDR
In a very large and homogeneous population sample of a Mediterranean country, not only sibship size but also birth order was significantly associated with atopy, which supports the hypothesis that cross-infections acquired early in infancy or in later childhood might prevent development of atopy later in life.
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