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In vitro inhibition of Plasmodium falciparum by substances isolated from Amazonian antimalarial plants.
- V. F. de Andrade-Neto, A. M. Pohlit, +13 authors P. P. Vieira
- Biology, Medicine
- Memorias do Instituto Oswaldo Cruz
- 1 June 2007
In the present study, a quassinoid, neosergeolide, isolated from the roots and stems of Picrolemma sprucei (Simaroubaceae), the indole alkaloids ellipticine and aspidocarpine, isolated from the bark… Expand
New antimalarial and cytotoxic 4-nerolidylcatechol derivatives.
- A. C. Pinto, L. F. R. Silva, +9 authors A. M. Pohlit
- Chemistry, Medicine
- European journal of medicinal chemistry
- 1 June 2009
4-Nerolidylcatechol (1) was isolated from cultivated Pothomorphe peltata root on a multigram scale using straight-forward solvent extraction-column chromatography. New semi-synthetic derivatives of 1… Expand
Antimalarial Activities of Seaweeds Spatoglossum schroederi, Gracilaria birdiae and Udotea flabellum from Rio Grande do Norte Coast, Brazil
- G. Dantas, H. Rocha, Rodrigo C. N. Amorim, L. F. R. Silva, A. M. Pohlit, V. Andrade-Neto
- 31 December 2015
Data showed that the present bioactive components in these algae can be promising for the development of new antimalarial drugs; attempt to purify these compounds are in progress for furtherbiological assays. Expand